The Role of Cyclic Adenosine Monophosphate (cAMP) in Modulating Glucocorticoid Receptor Signaling and Its Implications on Glucocorticoid-Related Collagen Loss

The Role of Cyclic Adenosine Monophosphate (cAMP) in Modulating Glucocorticoid Receptor Signaling and Its Implications on Glucocorticoid-Related Collagen Loss

Glucocorticoid receptors (GRs) play a pivotal role in the stress response of the body, but overactivation can disrupt normal physiological functions. This study explores the role of cyclic adenosine monophosphate (cAMP) in GR activation and the associated mechanisms. We initially used the human embr...

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Bibliographic Details
Main Authors: Wesuk Kang, Dabin Choi, Jiyun Roh, Yearim Jung, Yoojeong Ha, Suhjin Yang, Taesun Park
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
glucocorticoid
glucocorticoid receptor
cAMP
ERK
collagen
Online Access:https://www.mdpi.com/1422-0067/24/12/10180

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