The cytotoxicity of polycationic iron oxide nanoparticles: Common endpoint assays and alternative approaches for improved understanding of cellular response mechanism

The cytotoxicity of polycationic iron oxide nanoparticles: Common endpoint assays and alternative approaches for improved understanding of cellular response mechanism

<p>Abstract</p> <p>Background</p> <p>Iron oxide magnetic nanoparticles (MNP's) have an increasing number of biomedical applications. As such in vitro characterisation is essential to ensure the bio-safety of these particles. Little is known on the cellular interact...

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Bibliographic Details
Main Authors: Hoskins Clare, Cuschieri Alfred, Wang Lijun
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Journal of Nanobiotechnology
Subjects:
Magnetic nanoparticle
Cellular interaction
Cell membrane
Cytotoxicity
Cell viability assay
Atomic force microscopy
Zeta potential
Online Access:http://www.jnanobiotechnology.com/content/10/1/15

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