Silica nanoparticles inhibit the cation channel TRPV4 in airway epithelial cells

Silica nanoparticles inhibit the cation channel TRPV4 in airway epithelial cells

Abstract Background Silica nanoparticles (SiNPs) have numerous beneficial properties and are extensively used in cosmetics and food industries as anti-caking, densifying and hydrophobic agents. However, the increasing exposure levels experienced by the general population and the ability of SiNPs to...

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Bibliographic Details
Main Authors: Alicia Sanchez, Julio L. Alvarez, Kateryna Demydenko, Carole Jung, Yeranddy A. Alpizar, Julio Alvarez-Collazo, Stevan M. Cokic, Miguel A. Valverde, Peter H. Hoet, Karel Talavera
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Particle and Fibre Toxicology
Subjects:
silica nanoparticles
TRPV4
GSK1016790A
epithelial cells
ciliary beat frequency
Online Access:http://link.springer.com/article/10.1186/s12989-017-0224-2

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