A transient homotypic interaction model for the influenza A virus NS1 protein effector domain.

Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal 'tail'. Although poorly understood, NS1 multimerization may autoregulate its actions. While RBD dimerization seems functi...

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Hlavní autoři: Philip S Kerry, Juan Ayllon, Margaret A Taylor, Claudia Hass, Andrew Lewis, Adolfo García-Sastre, Richard E Randall, Benjamin G Hale, Rupert J Russell
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2011-03-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3065461?pdf=render