Comparison of the Effects of Intra-articular Hyaluronic Acid and Tenoxicam on Pain and Knee Joint Functions in Knee Osteoarthritis
Aim: The objective of this study is comparing the effects of intra-articular hyaluronic acid (HA) and tenoxicam aplications on joint range of motion (ROM) and pain in patients with gonarthrosis.Patients and Method: This study was designed as prospective, non-randomized controlled, and single-blinded...
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| Format: | Article |
| Language: | English |
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Alanya Alaaddin Keykubat University
2018-11-01
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| Series: | Acta Medica Alanya |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/pub/medalanya/issue/39772/419286?publisher=alku |
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| author | Recai Özkılıç Tolgahan Kuru Serdar İpek Ekrem Keski̇n Cengiz Işık Yasin Emre Kaya |
| author_facet | Recai Özkılıç Tolgahan Kuru Serdar İpek Ekrem Keski̇n Cengiz Işık Yasin Emre Kaya |
| author_sort | Recai Özkılıç |
| collection | DOAJ |
| description | Aim: The objective of this study is comparing the effects of
intra-articular hyaluronic acid (HA) and tenoxicam aplications on joint range
of motion (ROM) and pain in patients with gonarthrosis.Patients
and Method: This study was designed
as prospective, non-randomized controlled, and single-blinded trial. 60
patients diagnosed with Grade II and Grade III osteoarthritis (OA) according to
the American College of Rheumatology (ACR) criteria were consecutively
enrolled. Patients were divided into two groups whereby the first group
received intra-articular HA three times a week and the other group received a
single dose intra-articular tenoxicam. Pre-treatment and after-treatment VAS
and ROM values of the groups were compared.Results: In the HA Group, 20 patients (66.6%) were female, 10
patients (33.3%) were male and the mean age of them was 59.6 years (range 45-75
years). In the Tenoxicam Group, 24 patients (80%) were female, 6 (20%) patients
were male, and the average age of this group was 61.5 years (range 45-75
years). VAS scores knee flexion and extension ROM values on the 1st day, the
15th day, the 1st month,the2nd month, and the 3rd month after the treatment,
significantly improved in both groups (p <0.05). When the change levels in
the groups were compared, the changes in the Tenoxicam Group were more
prominent in the early period, but there was no difference between the two
groups in terms of the 3rd-month values after the treatment (p> 0.05).
Conclusion: It was seen that intra-articular HA and tenoxicam administration
seem to be effective and reliable methods in Grade 2-3 knee OA patients; but
tenoxicam was more effective in reducing pain and relieving joint movements
compared to HA injection in the early periods. |
| first_indexed | 2024-04-10T10:16:23Z |
| format | Article |
| id | doaj.art-1e57fc2ac58a49c69cff22c4365a05a8 |
| institution | Directory Open Access Journal |
| issn | 2587-0319 |
| language | English |
| last_indexed | 2024-04-10T10:16:23Z |
| publishDate | 2018-11-01 |
| publisher | Alanya Alaaddin Keykubat University |
| record_format | Article |
| series | Acta Medica Alanya |
| spelling | doaj.art-1e57fc2ac58a49c69cff22c4365a05a82023-02-15T16:21:49ZengAlanya Alaaddin Keykubat UniversityActa Medica Alanya2587-03192018-11-012314915810.30565/medalanya.419286727Comparison of the Effects of Intra-articular Hyaluronic Acid and Tenoxicam on Pain and Knee Joint Functions in Knee OsteoarthritisRecai ÖzkılıçTolgahan KuruSerdar İpekEkrem Keski̇nCengiz IşıkYasin Emre KayaAim: The objective of this study is comparing the effects of intra-articular hyaluronic acid (HA) and tenoxicam aplications on joint range of motion (ROM) and pain in patients with gonarthrosis.Patients and Method: This study was designed as prospective, non-randomized controlled, and single-blinded trial. 60 patients diagnosed with Grade II and Grade III osteoarthritis (OA) according to the American College of Rheumatology (ACR) criteria were consecutively enrolled. Patients were divided into two groups whereby the first group received intra-articular HA three times a week and the other group received a single dose intra-articular tenoxicam. Pre-treatment and after-treatment VAS and ROM values of the groups were compared.Results: In the HA Group, 20 patients (66.6%) were female, 10 patients (33.3%) were male and the mean age of them was 59.6 years (range 45-75 years). In the Tenoxicam Group, 24 patients (80%) were female, 6 (20%) patients were male, and the average age of this group was 61.5 years (range 45-75 years). VAS scores knee flexion and extension ROM values on the 1st day, the 15th day, the 1st month,the2nd month, and the 3rd month after the treatment, significantly improved in both groups (p <0.05). When the change levels in the groups were compared, the changes in the Tenoxicam Group were more prominent in the early period, but there was no difference between the two groups in terms of the 3rd-month values after the treatment (p> 0.05). Conclusion: It was seen that intra-articular HA and tenoxicam administration seem to be effective and reliable methods in Grade 2-3 knee OA patients; but tenoxicam was more effective in reducing pain and relieving joint movements compared to HA injection in the early periods.https://dergipark.org.tr/en/pub/medalanya/issue/39772/419286?publisher=alkuosteoartrittenoksikamhyalüronik asitosteoarthritistenoxicamhyaluronic acid |
| spellingShingle | Recai Özkılıç Tolgahan Kuru Serdar İpek Ekrem Keski̇n Cengiz Işık Yasin Emre Kaya Comparison of the Effects of Intra-articular Hyaluronic Acid and Tenoxicam on Pain and Knee Joint Functions in Knee Osteoarthritis Acta Medica Alanya osteoartrit tenoksikam hyalüronik asit osteoarthritis tenoxicam hyaluronic acid |
| title | Comparison of the Effects of Intra-articular Hyaluronic Acid and Tenoxicam on Pain and Knee Joint Functions in Knee Osteoarthritis |
| title_full | Comparison of the Effects of Intra-articular Hyaluronic Acid and Tenoxicam on Pain and Knee Joint Functions in Knee Osteoarthritis |
| title_fullStr | Comparison of the Effects of Intra-articular Hyaluronic Acid and Tenoxicam on Pain and Knee Joint Functions in Knee Osteoarthritis |
| title_full_unstemmed | Comparison of the Effects of Intra-articular Hyaluronic Acid and Tenoxicam on Pain and Knee Joint Functions in Knee Osteoarthritis |
| title_short | Comparison of the Effects of Intra-articular Hyaluronic Acid and Tenoxicam on Pain and Knee Joint Functions in Knee Osteoarthritis |
| title_sort | comparison of the effects of intra articular hyaluronic acid and tenoxicam on pain and knee joint functions in knee osteoarthritis |
| topic | osteoartrit tenoksikam hyalüronik asit osteoarthritis tenoxicam hyaluronic acid |
| url | https://dergipark.org.tr/en/pub/medalanya/issue/39772/419286?publisher=alku |
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