Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II

Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II

Carbonic anhydrase II (CAII) is a metalloenzyme that catalyzes the reversible hydration/dehydration of CO<sub>2</sub>/HCO<sub>3</sub><sup>−</sup>. In addition, CAII is attributed to other catalytic reactions, including esterase activity. Aspirin (acetyl-salicylic...

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Bibliographic Details
Main Authors:	Jacob Andring, Jacob Combs, Robert McKenna
Format:	Article
Language:	English
Published:	MDPI AG 2020-03-01
Series:	Biomolecules
Subjects:	carbonic anhydrase Aspirin salicylic acid esterase X-ray crystallography
Online Access:	https://www.mdpi.com/2218-273X/10/4/527

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