NTD Diagnostics for Disease Elimination: A Review

Neglected Tropical Diseases (NTDs) marked out for disease elimination provide a lens through which to explore the changing status of diagnosis in global health. This paper reports on the findings of a scoping review, which set out to explore the main debates around diagnosis for the elimination of N...

Full description

Bibliographic Details
Main Author: Emma Michelle Taylor
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/10/6/375
_version_ 1797565993643409408
author Emma Michelle Taylor
author_facet Emma Michelle Taylor
author_sort Emma Michelle Taylor
collection DOAJ
description Neglected Tropical Diseases (NTDs) marked out for disease elimination provide a lens through which to explore the changing status of diagnosis in global health. This paper reports on the findings of a scoping review, which set out to explore the main debates around diagnosis for the elimination of NTDs, including the multiple roles diagnostic technologies are being ascribed and the ideal characteristics of tests. It also attempts to summarise the state of diagnosis for three NTDs with elimination goals. The review places special emphasis on point-of-care testing in acknowledgement of the remote and underserved areas where NTDs proliferate. Early NTD campaigns were largely focused on attack phase planning, whereby a similar set of interventions could be transplanted anywhere. Now, with elimination goals in sight, strategies must be tailored to local settings if they are to attain and sustain success. Diagnostic data helps with local adaptation and is increasingly used for programmatic decision-making. The review finds that elimination goals reframe whom diagnosis is for and the myriad roles diagnostics can play. The exigencies of elimination also serve to highlight deficiencies in the current diagnostic arsenal and development pipeline for many NTDs. Moving forward, a guiding framework is needed to drive research and stimulate investment in diagnosis to support NTD goals.
first_indexed 2024-03-10T19:20:32Z
format Article
id doaj.art-1e5dc227faba4ec9a7891094be47ec4d
institution Directory Open Access Journal
issn 2075-4418
language English
last_indexed 2024-03-10T19:20:32Z
publishDate 2020-06-01
publisher MDPI AG
record_format Article
series Diagnostics
spelling doaj.art-1e5dc227faba4ec9a7891094be47ec4d2023-11-20T03:00:07ZengMDPI AGDiagnostics2075-44182020-06-0110637510.3390/diagnostics10060375NTD Diagnostics for Disease Elimination: A ReviewEmma Michelle Taylor0Department of Social Anthropology, University of Edinburgh, Edinburgh EH8 9LD, UKNeglected Tropical Diseases (NTDs) marked out for disease elimination provide a lens through which to explore the changing status of diagnosis in global health. This paper reports on the findings of a scoping review, which set out to explore the main debates around diagnosis for the elimination of NTDs, including the multiple roles diagnostic technologies are being ascribed and the ideal characteristics of tests. It also attempts to summarise the state of diagnosis for three NTDs with elimination goals. The review places special emphasis on point-of-care testing in acknowledgement of the remote and underserved areas where NTDs proliferate. Early NTD campaigns were largely focused on attack phase planning, whereby a similar set of interventions could be transplanted anywhere. Now, with elimination goals in sight, strategies must be tailored to local settings if they are to attain and sustain success. Diagnostic data helps with local adaptation and is increasingly used for programmatic decision-making. The review finds that elimination goals reframe whom diagnosis is for and the myriad roles diagnostics can play. The exigencies of elimination also serve to highlight deficiencies in the current diagnostic arsenal and development pipeline for many NTDs. Moving forward, a guiding framework is needed to drive research and stimulate investment in diagnosis to support NTD goals.https://www.mdpi.com/2075-4418/10/6/375diagnosisneglected tropical diseasedisease eliminationpoint-of-care diagnostics
spellingShingle Emma Michelle Taylor
NTD Diagnostics for Disease Elimination: A Review
Diagnostics
diagnosis
neglected tropical disease
disease elimination
point-of-care diagnostics
title NTD Diagnostics for Disease Elimination: A Review
title_full NTD Diagnostics for Disease Elimination: A Review
title_fullStr NTD Diagnostics for Disease Elimination: A Review
title_full_unstemmed NTD Diagnostics for Disease Elimination: A Review
title_short NTD Diagnostics for Disease Elimination: A Review
title_sort ntd diagnostics for disease elimination a review
topic diagnosis
neglected tropical disease
disease elimination
point-of-care diagnostics
url https://www.mdpi.com/2075-4418/10/6/375
work_keys_str_mv AT emmamichelletaylor ntddiagnosticsfordiseaseeliminationareview