Cutaneous Toll-like Receptor 9 Pre-Defines Hydroxychloroquine Dosage in Patients with Both Discoid and Subacute Lupus Erythematosus

Cutaneous Toll-like Receptor 9 Pre-Defines Hydroxychloroquine Dosage in Patients with Both Discoid and Subacute Lupus Erythematosus

<i>Background and Objectives</i>: Cutaneous lupus erythematosus (CLE) presents clinically heterogeneous manifestations, partially explained by the different expression of Toll-like receptors (TLRs) type 8 and 9, located to endosomal compartments where they are poised to recognize microbi...

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Bibliographic Details
Main Authors: Karolina A. Englert, Grzegorz Dyduch, Agata Kłosowicz, Magdalena Spałkowska, Andrzej Kazimierz Jaworek, Kamila Migacz-Gruszka, Aleksandra Jarosz-Chudek, Santo Raffaele Mercuri, Joanna Szpor, Gianluigi Mazzoccoli, Giovanni Damiani, Anna Wojas-Pelc
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Medicina
Subjects:
cutaneous lupus erythematosus
discoid lupus erythematosus (DLE)
subacute cutaneous lupus erythematosus (SCLE)
CLASI
hydroxychloroquine response
precision medicine
Online Access:https://www.mdpi.com/1648-9144/59/11/2022

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