Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Wnt3 proteins are lipidated and glycosylated signaling molecules that play an important role in zebrafish neural patterning and brain development. However, the transport mechanism of lipid-modified Wnts through the hydrophilic extracellular environment for long-range action remains unresolved. Here...

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Bibliographic Details
Main Authors:	Sapthaswaran Veerapathiran, Cathleen Teh, Shiwen Zhu, Indira Kartigayen, Vladimir Korzh, Paul T Matsudaira, Thorsten Wohland
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2020-11-01
Series:	eLife
Subjects:	Wnt3 Frizzled fluorescence correlation spectroscopy Fluorescence recovery after photobleaching Lrp5 extracellular diffusion
Online Access:	https://elifesciences.org/articles/59489

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