Characterization of a rhabdomyosarcoma reveals a critical role for SMG7 in cancer cell viability and tumor growth
Abstract Soft-tissue sarcomas (STSs) are a rare and diverse group of mesenchymal cancers plagued with aggression, poor response to systemic therapy, and high rates of recurrence. Although STSs generally have low mutational burdens, the most commonly mutated genes are tumor suppressors, which frequen...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-36568-5 |