Bullous Pemphigoid Causing Successive Emergency Department Visits
Case Presentation: In this case presentation, an 84-year-old male with Fitzpatrick type IV skin tone experienced blistering due to bullous pemphigoid (BP), first on the distal upper left extremity and then on the distal lower extremities, chest, and back. These symptoms resulted in three visits to t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
eScholarship Publishing, University of California
2023-10-01
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| Series: | Clinical Practice and Cases in Emergency Medicine |
| Online Access: | https://escholarship.org/uc/item/5g51j4wt |
| _version_ | 1797306644452868096 |
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| author | Edmund Hsu Andrew T. Kinoshita C. Eric McCoy |
| author_facet | Edmund Hsu Andrew T. Kinoshita C. Eric McCoy |
| author_sort | Edmund Hsu |
| collection | DOAJ |
| description | Case Presentation: In this case presentation, an 84-year-old male with Fitzpatrick type IV skin tone experienced blistering due to bullous pemphigoid (BP), first on the distal upper left extremity and then on the distal lower extremities, chest, and back. These symptoms resulted in three visits to the emergency department within a month, as well as an episode of hospitalization. Despite treatment, the blistering did not resolve until future outpatient care with dermatology. Discussion: Bullous pemphigoid is a rare autoimmune disease where autoantibodies target hemidesmosomal proteins causing basement membrane destruction and tense subepithelial bullae with pruritus. While uncommon, the incidence of BP is increasing. Bullous pemphigoid tends to affect older adults, appearing as a rash prior to bullae formation on the abdomen, extremities, groin, axillae, or mucosa. Bullous pemphigoid may also be drug-related with atypical symptoms. Diagnosis of BP should be based on immunopathology, and initial treatment of BP is through corticosteroid or doxycycline. |
| first_indexed | 2024-03-08T00:44:52Z |
| format | Article |
| id | doaj.art-1e7194a1dd6847eeaa754982a7af906a |
| institution | Directory Open Access Journal |
| issn | 2474-252X |
| language | English |
| last_indexed | 2024-03-08T00:44:52Z |
| publishDate | 2023-10-01 |
| publisher | eScholarship Publishing, University of California |
| record_format | Article |
| series | Clinical Practice and Cases in Emergency Medicine |
| spelling | doaj.art-1e7194a1dd6847eeaa754982a7af906a2024-02-15T11:39:21ZengeScholarship Publishing, University of CaliforniaClinical Practice and Cases in Emergency Medicine2474-252X2023-10-017426827010.5811/cpcem.14151415Bullous Pemphigoid Causing Successive Emergency Department VisitsEdmund Hsu0Andrew T. Kinoshita1C. Eric McCoy2University of California Irvine, Department of Emergency Medicine, Orange, CaliforniaUniversity of California Irvine, School of Medicine, Orange, CaliforniaUniversity of California Irvine, Department of Emergency Medicine, Orange, CaliforniaCase Presentation: In this case presentation, an 84-year-old male with Fitzpatrick type IV skin tone experienced blistering due to bullous pemphigoid (BP), first on the distal upper left extremity and then on the distal lower extremities, chest, and back. These symptoms resulted in three visits to the emergency department within a month, as well as an episode of hospitalization. Despite treatment, the blistering did not resolve until future outpatient care with dermatology. Discussion: Bullous pemphigoid is a rare autoimmune disease where autoantibodies target hemidesmosomal proteins causing basement membrane destruction and tense subepithelial bullae with pruritus. While uncommon, the incidence of BP is increasing. Bullous pemphigoid tends to affect older adults, appearing as a rash prior to bullae formation on the abdomen, extremities, groin, axillae, or mucosa. Bullous pemphigoid may also be drug-related with atypical symptoms. Diagnosis of BP should be based on immunopathology, and initial treatment of BP is through corticosteroid or doxycycline.https://escholarship.org/uc/item/5g51j4wt |
| spellingShingle | Edmund Hsu Andrew T. Kinoshita C. Eric McCoy Bullous Pemphigoid Causing Successive Emergency Department Visits Clinical Practice and Cases in Emergency Medicine |
| title | Bullous Pemphigoid Causing Successive Emergency Department Visits |
| title_full | Bullous Pemphigoid Causing Successive Emergency Department Visits |
| title_fullStr | Bullous Pemphigoid Causing Successive Emergency Department Visits |
| title_full_unstemmed | Bullous Pemphigoid Causing Successive Emergency Department Visits |
| title_short | Bullous Pemphigoid Causing Successive Emergency Department Visits |
| title_sort | bullous pemphigoid causing successive emergency department visits |
| url | https://escholarship.org/uc/item/5g51j4wt |
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