Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm

The study included 15 patients with coronary heart disease (CHD), post-infarction cardiosclerosis, and chronic left ventricular (LV) aneurysm. All patients underwent interventional myocardial revascularization and Dor aneurysmectomy. Myocardial scintigraphy with 99mTc-MYOVLEW was performed at baseli...

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Main Authors: E. V. Makarova, S. M. Minin, V. I. Chernov, E. V. Krivoshchekov, Yu. B. Lishmanov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2007-04-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2073
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author E. V. Makarova
S. M. Minin
V. I. Chernov
E. V. Krivoshchekov
Yu. B. Lishmanov
author_facet E. V. Makarova
S. M. Minin
V. I. Chernov
E. V. Krivoshchekov
Yu. B. Lishmanov
author_sort E. V. Makarova
collection DOAJ
description The study included 15 patients with coronary heart disease (CHD), post-infarction cardiosclerosis, and chronic left ventricular (LV) aneurysm. All patients underwent interventional myocardial revascularization and Dor aneurysmectomy. Myocardial scintigraphy with 99mTc-MYOVLEW was performed at baseline (during nitroglycerine test and at rest), and 3-4 weeks after revascularization (at rest). According to baseline scintigraphy at rest data, 35% of the segments were hypoperfused, and in 20% the agent did not accumulate. After sublingual nitroglycerine administration, hypo- and non-perfused segment percentage reduced to 24%> and 11%, respectively, after revascularization - to 24% and 11%. Single-photon emission computed tomography with 99mTc-MYOVLEW, combined with sublingual nitroglycerin test, identifies viable myocardial zones in post-infarction LV aneurism area and might be used for predicting post-rev ascularization LF function recovery. Статья написана при поддержке Регионального общественного фонда содействия отечественной медицине
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spelling doaj.art-1e72d55e406047fca0aca9835a5ba0762023-03-29T21:23:14Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202007-04-010236401828Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysmE. V. Makarova0S. M. Minin1V. I. Chernov2E. V. Krivoshchekov3Yu. B. Lishmanov4Научно-исследовательский институт кардиологии Томского научного центра РАМННаучно-исследовательский институт кардиологии Томского научного центра РАМННаучно-исследовательский институт кардиологии Томского научного центра РАМННаучно-исследовательский институт кардиологии Томского научного центра РАМННаучно-исследовательский институт кардиологии Томского научного центра РАМНThe study included 15 patients with coronary heart disease (CHD), post-infarction cardiosclerosis, and chronic left ventricular (LV) aneurysm. All patients underwent interventional myocardial revascularization and Dor aneurysmectomy. Myocardial scintigraphy with 99mTc-MYOVLEW was performed at baseline (during nitroglycerine test and at rest), and 3-4 weeks after revascularization (at rest). According to baseline scintigraphy at rest data, 35% of the segments were hypoperfused, and in 20% the agent did not accumulate. After sublingual nitroglycerine administration, hypo- and non-perfused segment percentage reduced to 24%> and 11%, respectively, after revascularization - to 24% and 11%. Single-photon emission computed tomography with 99mTc-MYOVLEW, combined with sublingual nitroglycerin test, identifies viable myocardial zones in post-infarction LV aneurism area and might be used for predicting post-rev ascularization LF function recovery. Статья написана при поддержке Регионального общественного фонда содействия отечественной медицинеhttps://russjcardiol.elpub.ru/jour/article/view/2073myocardial perfusionhibernationviabilitycoronary heart diseasenitroglycerin
spellingShingle E. V. Makarova
S. M. Minin
V. I. Chernov
E. V. Krivoshchekov
Yu. B. Lishmanov
Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
Российский кардиологический журнал
myocardial perfusion
hibernation
viability
coronary heart disease
nitroglycerin
title Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_full Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_fullStr Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_full_unstemmed Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_short Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm
title_sort scintigraphy assessment of ischemic myocardial viability in patients with post infarction left ventricular aneurysm
topic myocardial perfusion
hibernation
viability
coronary heart disease
nitroglycerin
url https://russjcardiol.elpub.ru/jour/article/view/2073
work_keys_str_mv AT evmakarova scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm
AT smminin scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm
AT vichernov scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm
AT evkrivoshchekov scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm
AT yublishmanov scintigraphyassessmentofischemicmyocardialviabilityinpatientswithpostinfarctionleftventricularaneurysm