The daf-7(e1372) mutation rescues dauer formation defects seen in C. elegans unc-33 mutants

The daf-7(e1372) mutation rescues dauer formation defects seen in C. elegans unc-33 mutants

Collapsin response mediator protein-2 (CRMP2) in humans, UNC-33 in C. elegans, is a molecule that mediates axonal outgrowth and stability. UNC-33/CRMP2 has been hypothesized as a potential drug target for treating Alzheimer’s and other neurodegenerative diseases, which can often be attributed in par...

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Bibliographic Details
Main Authors: Alexia Samaro, Alejandra Cristancho, Alexis Rivas, Ruby Valtierra, Skye Beck, Jason Cantu, Maria Miranda, Arianna Vacio, Oscar Cardenas Muedano, Andrea Holgado
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Physiology
Subjects:
dauer
TGF-β
UNC-33
C. elegans
locomotion
axonal outgrowth
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.975878/full

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