Humoral immunoprofiling identifies novel biomarkers and an immune suppressive autoantibody phenotype at the site of disease in pancreatic ductal adenocarcinoma

Humoral immunoprofiling identifies novel biomarkers and an immune suppressive autoantibody phenotype at the site of disease in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous cancer, with minimal response to therapeutic intervention and with 85% of cases diagnosed at an advanced stage due to lack of early symptoms, highlighting the importance of understanding PDAC immunology in greater detail. Here, we applied an...

Full description

Bibliographic Details
Main Authors: Pamela Winnie M. Maimela, Muneerah Smith, Andrew J. M. Nel, Suba Dharshanan P. Bernam, Eduard G. Jonas, Jonathan M. Blackburn
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
protein microarray
autoantibody biomarkers
antibody glycosylation
cancer testis antigen
pancreatic ductal adenocarcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1330419/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1330419/full

Similar Items