EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLS
The effect of garden cress ( Lepidium sativum ) on mitotic index (MI) and formation of micronuclei (Mn) in bone marrow cells of white mice was studied , in addition to the study of the counter effect of plant juice on MI disruption and Mn induction by cyclophosphamide (Cp) . The results indicated t...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Arabic |
| Published: |
College of Agriculture
2009-09-01
|
| Series: | Mesopotamia Journal of Agriculture |
| Online Access: | https://magrj.mosuljournals.com/article_27436_03f2f491836973aeb23a2a2244c9af49.pdf |
| _version_ | 1818024724669661184 |
|---|---|
| author | Ilham A. Khalaf |
| author_facet | Ilham A. Khalaf |
| author_sort | Ilham A. Khalaf |
| collection | DOAJ |
| description | The effect of garden cress ( Lepidium sativum ) on mitotic index (MI) and formation of micronuclei (Mn) in bone marrow cells of white mice was studied , in addition to the study of the counter effect of plant juice on MI disruption and Mn induction by cyclophosphamide (Cp) . The results indicated that Cp reduced the MI to level of positive control after 2 , 4 , 6 days with significant differences compared to the negative control (P<0.01) , while the plant juice 0.1 , 0.25 , 0.5 ml / animal administrated orally had no effect and the MI values were similar to the negative control. Oral administration of juice before administration of the mutagen (R/Cp) or with the mutagen (R+Cp) helped the tissues to preserve their MI values at natural level. Administration of juice after the mutagen (Cp/R) resulted in reduction of MI values compared to the natural values with statistical significant difference (P<0.01) |
| first_indexed | 2024-12-10T04:04:46Z |
| format | Article |
| id | doaj.art-1e782b53587b44cda9c7f27fbedb352e |
| institution | Directory Open Access Journal |
| issn | 1815-316X 2224-9796 |
| language | Arabic |
| last_indexed | 2024-12-10T04:04:46Z |
| publishDate | 2009-09-01 |
| publisher | College of Agriculture |
| record_format | Article |
| series | Mesopotamia Journal of Agriculture |
| spelling | doaj.art-1e782b53587b44cda9c7f27fbedb352e2022-12-22T02:02:53ZaraCollege of AgricultureMesopotamia Journal of Agriculture1815-316X2224-97962009-09-0137312813710.33899/magrj.2009.2743627436EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLSIlham A. KhalafThe effect of garden cress ( Lepidium sativum ) on mitotic index (MI) and formation of micronuclei (Mn) in bone marrow cells of white mice was studied , in addition to the study of the counter effect of plant juice on MI disruption and Mn induction by cyclophosphamide (Cp) . The results indicated that Cp reduced the MI to level of positive control after 2 , 4 , 6 days with significant differences compared to the negative control (P<0.01) , while the plant juice 0.1 , 0.25 , 0.5 ml / animal administrated orally had no effect and the MI values were similar to the negative control. Oral administration of juice before administration of the mutagen (R/Cp) or with the mutagen (R+Cp) helped the tissues to preserve their MI values at natural level. Administration of juice after the mutagen (Cp/R) resulted in reduction of MI values compared to the natural values with statistical significant difference (P<0.01)https://magrj.mosuljournals.com/article_27436_03f2f491836973aeb23a2a2244c9af49.pdf |
| spellingShingle | Ilham A. Khalaf EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLS Mesopotamia Journal of Agriculture |
| title | EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLS |
| title_full | EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLS |
| title_fullStr | EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLS |
| title_full_unstemmed | EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLS |
| title_short | EFFECT OF GARDEN CRESS (LEPIDIUM SATIVUM ) ON MITOTIC INDEX AND FORMATION OF MICRONUCLEI IN WHITE MICE BONE MARROW CELLS |
| title_sort | effect of garden cress lepidium sativum on mitotic index and formation of micronuclei in white mice bone marrow cells |
| url | https://magrj.mosuljournals.com/article_27436_03f2f491836973aeb23a2a2244c9af49.pdf |
| work_keys_str_mv | AT ilhamakhalaf effectofgardencresslepidiumsativumonmitoticindexandformationofmicronucleiinwhitemicebonemarrowcells |