Effect of α-tubulin acetylation on the doublet microtubule structure

Acetylation of α-tubulin at the lysine 40 residue (αK40) by αTAT1/MEC-17 acetyltransferase modulates microtubule properties and occurs in most eukaryotic cells. Previous literatures suggest that acetylated microtubules are more stable and damage resistant. αK40 acetylation is the only known microtub...

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Bibliographic Details
Main Authors: Shun Kai Yang, Shintaroh Kubo, Corbin Steven Black, Katya Peri, Daniel Dai, Thibault Legal, Melissa Valente-Paterno, Jacek Gaertig, Khanh Huy Bui
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/92219