Modifying laboratory testing via home brew during the COVID-19 pandemic

Rapid development and deployment of diagnostic testing for COVID-19 have been a key component of the public health response to the pandemic. Out of necessity, academic and other clinical laboratories developed laboratory testing innovations for COVID-19 to meet clinical testing demands. In addition...

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Main Authors: Jeffery H. Moran, Larry Kessler, Jennifer Moylan, Craig Forrest, Karl Boehme, Josh Kennedy, Alex Greninger, Geoff Baird, Ericka Olgaard, Laura James
Format: Article
Language:English
Published: Cambridge University Press 2021-01-01
Series:Journal of Clinical and Translational Science
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2059866121000054/type/journal_article
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author Jeffery H. Moran
Larry Kessler
Jennifer Moylan
Craig Forrest
Karl Boehme
Josh Kennedy
Alex Greninger
Geoff Baird
Ericka Olgaard
Laura James
author_facet Jeffery H. Moran
Larry Kessler
Jennifer Moylan
Craig Forrest
Karl Boehme
Josh Kennedy
Alex Greninger
Geoff Baird
Ericka Olgaard
Laura James
author_sort Jeffery H. Moran
collection DOAJ
description Rapid development and deployment of diagnostic testing for COVID-19 have been a key component of the public health response to the pandemic. Out of necessity, academic and other clinical laboratories developed laboratory testing innovations for COVID-19 to meet clinical testing demands. In addition to constraints on local testing supplies and equipment, a rapidly changing regulatory framework created challenges for translational scientists. Illustrative examples of approaches used to develop laboratory tests during the early stages of the COVID-19 pandemic demonstrate effective team science approaches to this challenging clinical care and public health emergency. These experiences and the associated lessons learned are relevant to the development of public health response plans for future pandemics.
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spelling doaj.art-1e7b4dddc9664a1783729ea8d335c0f92023-03-09T12:31:04ZengCambridge University PressJournal of Clinical and Translational Science2059-86612021-01-01510.1017/cts.2021.5Modifying laboratory testing via home brew during the COVID-19 pandemicJeffery H. Moran0Larry Kessler1Jennifer Moylan2https://orcid.org/0000-0002-6065-5311Craig Forrest3https://orcid.org/0000-0002-6695-0936Karl Boehme4https://orcid.org/0000-0003-2691-9763Josh Kennedy5Alex Greninger6https://orcid.org/0000-0002-7443-0527Geoff Baird7Ericka Olgaard8Laura James9https://orcid.org/0000-0002-4266-3924Departments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USADepartment of Health Services, School of Public Health, University of Washington, Seattle, WA, USADepartment of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, USADepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USADepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USADepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USADepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington, USADepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington, USADepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USADepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USARapid development and deployment of diagnostic testing for COVID-19 have been a key component of the public health response to the pandemic. Out of necessity, academic and other clinical laboratories developed laboratory testing innovations for COVID-19 to meet clinical testing demands. In addition to constraints on local testing supplies and equipment, a rapidly changing regulatory framework created challenges for translational scientists. Illustrative examples of approaches used to develop laboratory tests during the early stages of the COVID-19 pandemic demonstrate effective team science approaches to this challenging clinical care and public health emergency. These experiences and the associated lessons learned are relevant to the development of public health response plans for future pandemics.https://www.cambridge.org/core/product/identifier/S2059866121000054/type/journal_articleDiagnostic testsCOVID-19laboratory developed tests
spellingShingle Jeffery H. Moran
Larry Kessler
Jennifer Moylan
Craig Forrest
Karl Boehme
Josh Kennedy
Alex Greninger
Geoff Baird
Ericka Olgaard
Laura James
Modifying laboratory testing via home brew during the COVID-19 pandemic
Journal of Clinical and Translational Science
Diagnostic tests
COVID-19
laboratory developed tests
title Modifying laboratory testing via home brew during the COVID-19 pandemic
title_full Modifying laboratory testing via home brew during the COVID-19 pandemic
title_fullStr Modifying laboratory testing via home brew during the COVID-19 pandemic
title_full_unstemmed Modifying laboratory testing via home brew during the COVID-19 pandemic
title_short Modifying laboratory testing via home brew during the COVID-19 pandemic
title_sort modifying laboratory testing via home brew during the covid 19 pandemic
topic Diagnostic tests
COVID-19
laboratory developed tests
url https://www.cambridge.org/core/product/identifier/S2059866121000054/type/journal_article
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