Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB

Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB

Abstract Background Mucopolysaccharidosis (MPS) IIIB, also known as Sanfilippo Syndrome B, is a devastating childhood disease. Unfortunately, there are currently no available treatments for MPS IIIB patients. Yet, animal models of lysosomal storage diseases have been valuable tools in identifying pr...

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Bibliographic Details
Main Authors: Katherine B. McCullough, Amanda Titus, Kate Reardon, Sara Conyers, Joseph D. Dougherty, Xia Ge, Joel R. Garbow, Patricia Dickson, Carla M. Yuede, Susan E. Maloney
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Sanfilippo B
Mucopolysaccharidosis IIIB
Lysosomal storage disorder
Ultrasonic vocalization
Gait
Fear conditioning
Online Access:https://doi.org/10.1186/s11689-024-09534-z

Internet

https://doi.org/10.1186/s11689-024-09534-z

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