Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)
In this report, we describe a case of a 5-year-old girl with poor growth and unresolving pneumonia. Bronchoscopy showed numerous endobronchial mucosal nodules, consisting of dense lymphoid infiltrates. Bacterial culture of the nodule biopsy suggested endobronchial actinomycosis. Genetic test confirm...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007123001041 |
| _version_ | 1797741454461763584 |
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| author | Kwan Fung Lam Shun Chan Lok Sang Kam Janette Kwok Pamela Pui-Wah Lee David Shu Yan Lam |
| author_facet | Kwan Fung Lam Shun Chan Lok Sang Kam Janette Kwok Pamela Pui-Wah Lee David Shu Yan Lam |
| author_sort | Kwan Fung Lam |
| collection | DOAJ |
| description | In this report, we describe a case of a 5-year-old girl with poor growth and unresolving pneumonia. Bronchoscopy showed numerous endobronchial mucosal nodules, consisting of dense lymphoid infiltrates. Bacterial culture of the nodule biopsy suggested endobronchial actinomycosis. Genetic test confirmed the diagnosis of APDS. |
| first_indexed | 2024-03-12T14:27:01Z |
| format | Article |
| id | doaj.art-1e80a1c486464437a6941fe0dd92fca4 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-03-12T14:27:01Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-1e80a1c486464437a6941fe0dd92fca42023-08-18T04:31:01ZengElsevierRespiratory Medicine Case Reports2213-00712023-01-0145101909Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)Kwan Fung Lam0Shun Chan1Lok Sang Kam2Janette Kwok3Pamela Pui-Wah Lee4David Shu Yan Lam5Department of Paediatrics and Adolescent Medicine, Caritas Medical Centre, Hong Kong, China; Corresponding author.Department of Surgery, Tuen Mun Hospital, Hong Kong, ChinaDepartment of Clinical Pathology, Tuen Mun Hospital, Hong Kong, ChinaDivision of Transplantation and Immunogenetics, Department of Pathology, Queen Mary Hospital, Hong Kong, ChinaDepartment of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, ChinaDepartment of Paediatrics and Adolescent Medicine, Tuen Mun Hospital, Hong Kong, ChinaIn this report, we describe a case of a 5-year-old girl with poor growth and unresolving pneumonia. Bronchoscopy showed numerous endobronchial mucosal nodules, consisting of dense lymphoid infiltrates. Bacterial culture of the nodule biopsy suggested endobronchial actinomycosis. Genetic test confirmed the diagnosis of APDS.http://www.sciencedirect.com/science/article/pii/S2213007123001041Endobronchial nodulesActivated phosphatidylinositol 3-kinase delta syndrome (APDS)Bronchial actinomycosisCobblestone airway |
| spellingShingle | Kwan Fung Lam Shun Chan Lok Sang Kam Janette Kwok Pamela Pui-Wah Lee David Shu Yan Lam Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS) Respiratory Medicine Case Reports Endobronchial nodules Activated phosphatidylinositol 3-kinase delta syndrome (APDS) Bronchial actinomycosis Cobblestone airway |
| title | Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS) |
| title_full | Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS) |
| title_fullStr | Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS) |
| title_full_unstemmed | Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS) |
| title_short | Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS) |
| title_sort | endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3 kinase delta syndrome apds |
| topic | Endobronchial nodules Activated phosphatidylinositol 3-kinase delta syndrome (APDS) Bronchial actinomycosis Cobblestone airway |
| url | http://www.sciencedirect.com/science/article/pii/S2213007123001041 |
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