Computational modeling of the molecular basis for the calcium-dependence of the mannuronan C-5 epimerase AvAlgE6 from Azotobacter vinelandii
The mannuronan C-5 epimerases catalyze epimerization of β-d-mannuronic acid to α-l-guluronic acid in alginate polymers. The seven extracellular Azotobacter vinelandii epimerases (AvAlgE1–7) are calcium-dependent, and calcium is essential for the structural integrity of their carbohydrate binding R-m...
Main Authors: | Margrethe Gaardløs, Anders Lervik, Sergey A. Samsonov |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037023001228 |
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