Extractionno-Photometric Determination of Diabenol

Purpose: To study spectral and physicochemical characteristics Diabenol’s ion-associates and extraction equilibria and to develop a method for determination of small amounts of substance in the presence of other compounds.Materials and Methods: An extraction-photometric method of analysis was chosen...

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Main Authors: O. I. Ascalepova, I. E. Nicanorova, V. A. Anisymova
Format: Article
Language:English
Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 2011-12-01
Series:Медицинский вестник Юга России
Subjects:
Online Access:https://www.medicalherald.ru/jour/article/view/1244
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author O. I. Ascalepova
I. E. Nicanorova
V. A. Anisymova
author_facet O. I. Ascalepova
I. E. Nicanorova
V. A. Anisymova
author_sort O. I. Ascalepova
collection DOAJ
description Purpose: To study spectral and physicochemical characteristics Diabenol’s ion-associates and extraction equilibria and to develop a method for determination of small amounts of substance in the presence of other compounds.Materials and Methods: An extraction-photometric method of analysis was chosen because it is widely used in pharmaceutical analysis and find a use in chemico-toxiological researches.Results: It was developed a method of extraction-photometric detection of dosage forms with small amounts of diabenol in the presence of substance that prevent its detection with the methods of titrimetric analysis and ultraviolet spectroscopy. The investigation showed that the use of chloroform as extraction agent of diabenol ion-associates and anionic dyes is optimal.Summary: This method makes possible to detect the basic substance with high precision and repeatability of measurements.
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spelling doaj.art-1e8d3e45b43d470298b7fe1eac0ebe652022-12-22T04:18:31ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762011-12-01042428731Extractionno-Photometric Determination of DiabenolO. I. Ascalepova0I. E. Nicanorova1V. A. Anisymova2Rostov State Medical University; South Federal UniversityRostov State Medical UniversityResearch Institute of Physical and Organic Chemistry of South Federal UniversityPurpose: To study spectral and physicochemical characteristics Diabenol’s ion-associates and extraction equilibria and to develop a method for determination of small amounts of substance in the presence of other compounds.Materials and Methods: An extraction-photometric method of analysis was chosen because it is widely used in pharmaceutical analysis and find a use in chemico-toxiological researches.Results: It was developed a method of extraction-photometric detection of dosage forms with small amounts of diabenol in the presence of substance that prevent its detection with the methods of titrimetric analysis and ultraviolet spectroscopy. The investigation showed that the use of chloroform as extraction agent of diabenol ion-associates and anionic dyes is optimal.Summary: This method makes possible to detect the basic substance with high precision and repeatability of measurements.https://www.medicalherald.ru/jour/article/view/1244diabenolphysicochemical characteristicsanalysis
spellingShingle O. I. Ascalepova
I. E. Nicanorova
V. A. Anisymova
Extractionno-Photometric Determination of Diabenol
Медицинский вестник Юга России
diabenol
physicochemical characteristics
analysis
title Extractionno-Photometric Determination of Diabenol
title_full Extractionno-Photometric Determination of Diabenol
title_fullStr Extractionno-Photometric Determination of Diabenol
title_full_unstemmed Extractionno-Photometric Determination of Diabenol
title_short Extractionno-Photometric Determination of Diabenol
title_sort extractionno photometric determination of diabenol
topic diabenol
physicochemical characteristics
analysis
url https://www.medicalherald.ru/jour/article/view/1244
work_keys_str_mv AT oiascalepova extractionnophotometricdeterminationofdiabenol
AT ienicanorova extractionnophotometricdeterminationofdiabenol
AT vaanisymova extractionnophotometricdeterminationofdiabenol