Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and Cells

The idea of remote magnetic guiding is developed from the underlying physics of a concept that allows for bijective force generation over the inner volume of magnet systems. This concept can equally be implemented by electro- or permanent magnets. Here, permanent magnets are in the focus because the...

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Main Author: Peter Blümler
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/10/2708
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author Peter Blümler
author_facet Peter Blümler
author_sort Peter Blümler
collection DOAJ
description The idea of remote magnetic guiding is developed from the underlying physics of a concept that allows for bijective force generation over the inner volume of magnet systems. This concept can equally be implemented by electro- or permanent magnets. Here, permanent magnets are in the focus because they offer many advantages. The equations of magnetic fields and forces as well as velocities are derived in detail and physical limits are discussed. The special hydrodynamics of nanoparticle dispersions under these circumstances is reviewed and related to technical constraints. The possibility of 3D guiding and magnetic imaging techniques are discussed. Finally, the first results in guiding macroscopic objects, superparamagnetic nanoparticles, and cells with incorporated nanoparticles are presented. The constructed magnet systems allow for orientation, movement, and acceleration of magnetic objects and, in principle, can be scaled up to human size.
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spelling doaj.art-1e8f8506dd454422bde3eb1cb08da99e2023-11-22T17:47:53ZengMDPI AGCells2073-44092021-10-011010270810.3390/cells10102708Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and CellsPeter Blümler0Institute of Physics, University of Mainz, Staudingerweg 7, 55099 Mainz, GermanyThe idea of remote magnetic guiding is developed from the underlying physics of a concept that allows for bijective force generation over the inner volume of magnet systems. This concept can equally be implemented by electro- or permanent magnets. Here, permanent magnets are in the focus because they offer many advantages. The equations of magnetic fields and forces as well as velocities are derived in detail and physical limits are discussed. The special hydrodynamics of nanoparticle dispersions under these circumstances is reviewed and related to technical constraints. The possibility of 3D guiding and magnetic imaging techniques are discussed. Finally, the first results in guiding macroscopic objects, superparamagnetic nanoparticles, and cells with incorporated nanoparticles are presented. The constructed magnet systems allow for orientation, movement, and acceleration of magnetic objects and, in principle, can be scaled up to human size.https://www.mdpi.com/2073-4409/10/10/2708steeringmagnetic forcemagnetic drug targeting (MDT)nanoparticleSPIOferrofluid
spellingShingle Peter Blümler
Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and Cells
Cells
steering
magnetic force
magnetic drug targeting (MDT)
nanoparticle
SPIO
ferrofluid
title Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and Cells
title_full Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and Cells
title_fullStr Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and Cells
title_full_unstemmed Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and Cells
title_short Magnetic Guiding with Permanent Magnets: Concept, Realization and Applications to Nanoparticles and Cells
title_sort magnetic guiding with permanent magnets concept realization and applications to nanoparticles and cells
topic steering
magnetic force
magnetic drug targeting (MDT)
nanoparticle
SPIO
ferrofluid
url https://www.mdpi.com/2073-4409/10/10/2708
work_keys_str_mv AT peterblumler magneticguidingwithpermanentmagnetsconceptrealizationandapplicationstonanoparticlesandcells