Fluphenazine decanoate‐induced bradycardia: A case report

Abstract Sinus tachycardia and orthostatic hypotension have been so far reported among the negative cardiovascular complications of antipsychotic agents. This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration. The patient was a 29‐year‐old man, admitted t...

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Main Authors: Mahsa Kamali, Mehran Zarghami, Marzieh Azizi, Forouzan Elyasi
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Neuropsychopharmacology Reports
Subjects:
Online Access:https://doi.org/10.1002/npr2.12251
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author Mahsa Kamali
Mehran Zarghami
Marzieh Azizi
Forouzan Elyasi
author_facet Mahsa Kamali
Mehran Zarghami
Marzieh Azizi
Forouzan Elyasi
author_sort Mahsa Kamali
collection DOAJ
description Abstract Sinus tachycardia and orthostatic hypotension have been so far reported among the negative cardiovascular complications of antipsychotic agents. This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration. The patient was a 29‐year‐old man, admitted to the general teaching hospital in Sari, Iran, with a complaint of abdominal and gastric pain as well as weight loss following 7 months of fasting based on religious delusions. The patient developed bradycardia, 36 hours after fluphenazine decanoate administration. His pulse rate was also 46 beats per min (bpm). The antipsychotic medication was thus held and the patient did not take any drugs. On the 21st day after discontinuing this agent, the pulse rate reached 70 bpm. This case report notifies that much more attention should be paid to all patients before starting fluphenazine decanoate administration, and close cardiac monitoring must be done.
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spelling doaj.art-1e91945476324625ac3e0df0ee03b97c2022-12-22T02:56:57ZengWileyNeuropsychopharmacology Reports2574-173X2022-09-0142336837310.1002/npr2.12251Fluphenazine decanoate‐induced bradycardia: A case reportMahsa Kamali0Mehran Zarghami1Marzieh Azizi2Forouzan Elyasi3Pediatric Infectious Diseases Research Center Communicable Diseases Institute Mazandaran University of Medical Sciences Sari IranPsychiatry and Behavioral Sciences Research Center Addiction institute Mazandaran University of Medical Sciences Sari IranDepartment of Reproductive Health and Midwifery School of Nursing and Midwifery Tehran University of Medical Sciences Tehran IranDepartment of Psychiatry Faculty of Medicine Mazandaran University of Medical Sciences Sari IranAbstract Sinus tachycardia and orthostatic hypotension have been so far reported among the negative cardiovascular complications of antipsychotic agents. This study aimed to report a case with bradycardia induced by fluphenazine decanoate administration. The patient was a 29‐year‐old man, admitted to the general teaching hospital in Sari, Iran, with a complaint of abdominal and gastric pain as well as weight loss following 7 months of fasting based on religious delusions. The patient developed bradycardia, 36 hours after fluphenazine decanoate administration. His pulse rate was also 46 beats per min (bpm). The antipsychotic medication was thus held and the patient did not take any drugs. On the 21st day after discontinuing this agent, the pulse rate reached 70 bpm. This case report notifies that much more attention should be paid to all patients before starting fluphenazine decanoate administration, and close cardiac monitoring must be done.https://doi.org/10.1002/npr2.12251antipsychotic agentsbradycardiacase reportfluphenazine decanoate
spellingShingle Mahsa Kamali
Mehran Zarghami
Marzieh Azizi
Forouzan Elyasi
Fluphenazine decanoate‐induced bradycardia: A case report
Neuropsychopharmacology Reports
antipsychotic agents
bradycardia
case report
fluphenazine decanoate
title Fluphenazine decanoate‐induced bradycardia: A case report
title_full Fluphenazine decanoate‐induced bradycardia: A case report
title_fullStr Fluphenazine decanoate‐induced bradycardia: A case report
title_full_unstemmed Fluphenazine decanoate‐induced bradycardia: A case report
title_short Fluphenazine decanoate‐induced bradycardia: A case report
title_sort fluphenazine decanoate induced bradycardia a case report
topic antipsychotic agents
bradycardia
case report
fluphenazine decanoate
url https://doi.org/10.1002/npr2.12251
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AT marziehazizi fluphenazinedecanoateinducedbradycardiaacasereport
AT forouzanelyasi fluphenazinedecanoateinducedbradycardiaacasereport