Multi-omics analysis of the gut microbiome and metabolites associated with the psychoneurological symptom cluster in children with cancer receiving chemotherapy

Multi-omics analysis of the gut microbiome and metabolites associated with the psychoneurological symptom cluster in children with cancer receiving chemotherapy

Abstract Background Children with cancer receiving chemotherapy commonly report a cluster of psychoneurological symptoms (PNS), including pain, fatigue, anxiety, depression, and cognitive dysfunction. The role of the gut microbiome and its functional metabolites in PNS is rarely studied among childr...

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Bibliographic Details
Main Authors: Jinbing Bai, Ronald Eldridge, Madelyn Houser, Melissa Martin, Christie Powell, Kathryn S. Sutton, Hye In Noh, Yuhua Wu, Thomas Olson, Konstantinos T. Konstantinidis, Deborah W. Bruner
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
Children
Gut microbiome
Metabolome
Solid tumor
Chemotherapy
Multi-omics
Online Access:https://doi.org/10.1186/s12967-024-05066-1

Internet

https://doi.org/10.1186/s12967-024-05066-1

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