IL4I1 in M2-like macrophage promotes glioma progression and is a promising target for immunotherapy

IL4I1 in M2-like macrophage promotes glioma progression and is a promising target for immunotherapy

BackgroundGlioma is the prevailing malignant intracranial tumor, characterized by an abundance of macrophages. Specifically, the infiltrating macrophages often display the M2 subtype and are known as tumor-associated macrophages (TAMs). They have a critical role in promoting the oncogenic properties...

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Bibliographic Details
Main Authors: Feng Ye, Lichong Wang, Yuanyou Li, Chengyuan Dong, Liangxue Zhou, Jianguo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
IL4I1
glioma
tumor microenvironment
immunotherapy target
M2-like macrophage
TAM
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1338244/full

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