Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods?
Cardiovascular intervention for myocardial revascularization dominates modern treatment of ischaemic heart disease (IHD). Current efficiency and safety of this method could never be achieved without the development of antiplatelet agents that provide indispensable protection for endovascular interve...
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| Format: | Article |
| Language: | English |
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Endocrinology Research Centre
2013-09-01
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| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/95 |
| _version_ | 1797255259789197312 |
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| author | Irina Ziyatovna Bondarenko Irina Alexandrovna Shirshina |
| author_facet | Irina Ziyatovna Bondarenko Irina Alexandrovna Shirshina |
| author_sort | Irina Ziyatovna Bondarenko |
| collection | DOAJ |
| description | Cardiovascular intervention for myocardial revascularization dominates modern treatment of ischaemic heart disease (IHD). Current efficiency and safety of this method could never be achieved without the development of antiplatelet agents that provide indispensable protection for endovascular interventions. However, antithrombotic therapy is generally less effective in diabetes mellitus (DM), affecting prognosis for transcutaneous intervention. This trend is probably due to alteration of cellular homeostasis during hyperglycemia and correlates with its severity and persistence. This paper addresses modern understanding of factors affecting thrombogenesis in patients with DM. |
| first_indexed | 2024-03-08T15:21:00Z |
| format | Article |
| id | doaj.art-1ea0f7f3b1c54a869434ed4abbc4eb1e |
| institution | Directory Open Access Journal |
| issn | 2072-0351 2072-0378 |
| language | English |
| last_indexed | 2024-04-24T22:03:01Z |
| publishDate | 2013-09-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj.art-1ea0f7f3b1c54a869434ed4abbc4eb1e2024-03-20T11:47:58ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782013-09-01163586310.14341/2072-0351-9580Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods?Irina Ziyatovna Bondarenko0Irina Alexandrovna Shirshina1Endocrinology Research Centre, MoscowEndocrinology Research Centre, MoscowCardiovascular intervention for myocardial revascularization dominates modern treatment of ischaemic heart disease (IHD). Current efficiency and safety of this method could never be achieved without the development of antiplatelet agents that provide indispensable protection for endovascular interventions. However, antithrombotic therapy is generally less effective in diabetes mellitus (DM), affecting prognosis for transcutaneous intervention. This trend is probably due to alteration of cellular homeostasis during hyperglycemia and correlates with its severity and persistence. This paper addresses modern understanding of factors affecting thrombogenesis in patients with DM.https://www.dia-endojournals.ru/jour/article/view/95diabetes mellitushaemostasisischaemic heart diseaseplatelet functions |
| spellingShingle | Irina Ziyatovna Bondarenko Irina Alexandrovna Shirshina Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? Сахарный диабет diabetes mellitus haemostasis ischaemic heart disease platelet functions |
| title | Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
| title_full | Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
| title_fullStr | Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
| title_full_unstemmed | Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
| title_short | Mechanisms of thrombogenesis associated with diabetes mellitus: what defines the prognosis of invasive myocardial revascularization methods? |
| title_sort | mechanisms of thrombogenesis associated with diabetes mellitus what defines the prognosis of invasive myocardial revascularization methods |
| topic | diabetes mellitus haemostasis ischaemic heart disease platelet functions |
| url | https://www.dia-endojournals.ru/jour/article/view/95 |
| work_keys_str_mv | AT irinaziyatovnabondarenko mechanismsofthrombogenesisassociatedwithdiabetesmellituswhatdefinestheprognosisofinvasivemyocardialrevascularizationmethods AT irinaalexandrovnashirshina mechanismsofthrombogenesisassociatedwithdiabetesmellituswhatdefinestheprognosisofinvasivemyocardialrevascularizationmethods |