CADEXOMER VERSUS POVIDONE IODINE DRESSING IN CHRONIC LEG ULCERS- A PROSPECTIVE STUDY.

Background: In the present scenario the entire healthcare system has been overburdened with chronic wounds be it monetary wise or manpower requirements like nurses, doctors, etc. A chronic wound is being treated by many topical drugs which are prevailing in the market. So we considered this study...

Full description

Bibliographic Details
Main Authors: Ayush Raj, Ankit Raj, Sakshi Singh, Yasir Tajdar, Vibhuti Bhushan, Pawan Kumar Jha, K Abhishek
Format: Article
Language:English
Published: Student's Journal of Health Research 2023-03-01
Series:Student's Journal of Health Research Africa
Subjects:
Online Access:https://sjhresearchafrica.org/index.php/public-html/article/view/350
_version_ 1797854979414818816
author Ayush Raj
Ankit Raj
Sakshi Singh
Yasir Tajdar
Vibhuti Bhushan
Pawan Kumar Jha
K Abhishek
author_facet Ayush Raj
Ankit Raj
Sakshi Singh
Yasir Tajdar
Vibhuti Bhushan
Pawan Kumar Jha
K Abhishek
author_sort Ayush Raj
collection DOAJ
description Background: In the present scenario the entire healthcare system has been overburdened with chronic wounds be it monetary wise or manpower requirements like nurses, doctors, etc. A chronic wound is being treated by many topical drugs which are prevailing in the market. So we considered this study i.e. “the effect of cadexomer and providone iodine on chronic leg ulcers”. Objective:  The main and primary objective of this study was to compare the outcome of both, Cadexomer and povidone-iodine, about their effect on the treatment of leg ulcers. Methods: With 30 patients in each group, 30 patients with chronic wounds participated in this prospective study. As part of the statistical analysis, Pearson's Correlation Coefficient and the Student's Paired T-Test are used. Results: Patients who received cadexomer iodine ointment had a significantly (p<0.05) greater rate of wound healing, as well as a significantly lower level of bacterial overload and promotion of the creation of granulation tissue. Conclusion: The effect of cadexomer as a vector in combination with providone iodine ointment resulted in a higher rate of biofilm, slough, and debris reduction and a better rate of granulation tissue formation promotion, both of which increased the rate at which a wound heals and lowered the cost of managing chronic wounds. Recommendation:  It is recommended that the efficacy of the ointments (cadexomer and providone iodine) be researched for proper healing of ulcers and wounds in diabetic leg ulcers because a significant number of diabetic patients experience leg ulcers because, in this study, it was discovered that over 60 people suffered with the risk of leg ulcers.
first_indexed 2024-04-09T20:15:03Z
format Article
id doaj.art-1ea44edb803843a48f3c62fc354e8922
institution Directory Open Access Journal
issn 2709-9997
language English
last_indexed 2024-04-09T20:15:03Z
publishDate 2023-03-01
publisher Student's Journal of Health Research
record_format Article
series Student's Journal of Health Research Africa
spelling doaj.art-1ea44edb803843a48f3c62fc354e89222023-03-31T09:05:44ZengStudent's Journal of Health ResearchStudent's Journal of Health Research Africa2709-99972023-03-014310.51168/sjhrafrica.v4i3.350CADEXOMER VERSUS POVIDONE IODINE DRESSING IN CHRONIC LEG ULCERS- A PROSPECTIVE STUDY. Ayush Raj0 Ankit Raj1Sakshi Singh2Yasir Tajdar3Vibhuti Bhushan4 Pawan Kumar Jha5 K Abhishek6Department of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, IndiaDepartment of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, IndiaDepartment of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India Senior RDepartment of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, IndiaDepartment of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.Department of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, IndiaDepartment of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India Background: In the present scenario the entire healthcare system has been overburdened with chronic wounds be it monetary wise or manpower requirements like nurses, doctors, etc. A chronic wound is being treated by many topical drugs which are prevailing in the market. So we considered this study i.e. “the effect of cadexomer and providone iodine on chronic leg ulcers”. Objective:  The main and primary objective of this study was to compare the outcome of both, Cadexomer and povidone-iodine, about their effect on the treatment of leg ulcers. Methods: With 30 patients in each group, 30 patients with chronic wounds participated in this prospective study. As part of the statistical analysis, Pearson's Correlation Coefficient and the Student's Paired T-Test are used. Results: Patients who received cadexomer iodine ointment had a significantly (p<0.05) greater rate of wound healing, as well as a significantly lower level of bacterial overload and promotion of the creation of granulation tissue. Conclusion: The effect of cadexomer as a vector in combination with providone iodine ointment resulted in a higher rate of biofilm, slough, and debris reduction and a better rate of granulation tissue formation promotion, both of which increased the rate at which a wound heals and lowered the cost of managing chronic wounds. Recommendation:  It is recommended that the efficacy of the ointments (cadexomer and providone iodine) be researched for proper healing of ulcers and wounds in diabetic leg ulcers because a significant number of diabetic patients experience leg ulcers because, in this study, it was discovered that over 60 people suffered with the risk of leg ulcers. https://sjhresearchafrica.org/index.php/public-html/article/view/350CadexomerProvidone iodineUlcer Diabetes
spellingShingle Ayush Raj
Ankit Raj
Sakshi Singh
Yasir Tajdar
Vibhuti Bhushan
Pawan Kumar Jha
K Abhishek
CADEXOMER VERSUS POVIDONE IODINE DRESSING IN CHRONIC LEG ULCERS- A PROSPECTIVE STUDY.
Student's Journal of Health Research Africa
Cadexomer
Providone iodine
Ulcer
Diabetes
title CADEXOMER VERSUS POVIDONE IODINE DRESSING IN CHRONIC LEG ULCERS- A PROSPECTIVE STUDY.
title_full CADEXOMER VERSUS POVIDONE IODINE DRESSING IN CHRONIC LEG ULCERS- A PROSPECTIVE STUDY.
title_fullStr CADEXOMER VERSUS POVIDONE IODINE DRESSING IN CHRONIC LEG ULCERS- A PROSPECTIVE STUDY.
title_full_unstemmed CADEXOMER VERSUS POVIDONE IODINE DRESSING IN CHRONIC LEG ULCERS- A PROSPECTIVE STUDY.
title_short CADEXOMER VERSUS POVIDONE IODINE DRESSING IN CHRONIC LEG ULCERS- A PROSPECTIVE STUDY.
title_sort cadexomer versus povidone iodine dressing in chronic leg ulcers a prospective study
topic Cadexomer
Providone iodine
Ulcer
Diabetes
url https://sjhresearchafrica.org/index.php/public-html/article/view/350
work_keys_str_mv AT ayushraj cadexomerversuspovidoneiodinedressinginchroniclegulcersaprospectivestudy
AT ankitraj cadexomerversuspovidoneiodinedressinginchroniclegulcersaprospectivestudy
AT sakshisingh cadexomerversuspovidoneiodinedressinginchroniclegulcersaprospectivestudy
AT yasirtajdar cadexomerversuspovidoneiodinedressinginchroniclegulcersaprospectivestudy
AT vibhutibhushan cadexomerversuspovidoneiodinedressinginchroniclegulcersaprospectivestudy
AT pawankumarjha cadexomerversuspovidoneiodinedressinginchroniclegulcersaprospectivestudy
AT kabhishek cadexomerversuspovidoneiodinedressinginchroniclegulcersaprospectivestudy