Cinnamic acid mitigates left ventricular hypertrophy and heart failure in part through modulating FTO-dependent N6-methyladenosine RNA modification in cardiomyocytes

Cinnamic acid mitigates left ventricular hypertrophy and heart failure in part through modulating FTO-dependent N6-methyladenosine RNA modification in cardiomyocytes

Left ventricular hypertrophy leads to heart failure, a serious medical condition associated with high rates of hospitalization and mortality. Limited success with the existing pharmacological treatments necessitates the development of mechanisms-based new therapies to better control the progression...

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Bibliographic Details
Main Authors:	Yimeng Cui, Peiwei Wang, Mengli Li, Yujue Wang, Xinmiao Tang, Jingang Cui, Yu Chen, Teng Zhang
Format:	Article
Language:	English
Published:	Elsevier 2023-09-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Left ventricular hypertrophy Heart failure Mitochondria N6-methyladenosine RNA modification FTO Cinnamic acid
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332223009599

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