Identification of histone malonylation in the human fetal brain and implications for diabetes‐induced neural tube defects

Identification of histone malonylation in the human fetal brain and implications for diabetes‐induced neural tube defects

Abstract Background Neural tube defects (NTDs) are severe congenital malformations. Diabetes during pregnancy is a risk factor for NTDs, but its mechanism remains elusive. Emerging evidence suggests that protein malonylation is involved in diabetes. Here, we report the correlation between histone ly...

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Bibliographic Details
Main Authors: Qin Zhang, Tanxi Cai, Zonghui Xiao, Dan Li, Chunlei Wan, Xiaodai Cui, Baoling Bai
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
diabetes
histone lysine malonylation
mass spectrometry
neural tube defects
Online Access:https://doi.org/10.1002/mgg3.1403

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