Synthesis, characterization and antitumor activity of the germanium-quercetin complex
Quercetin-germanium (Ge) (IV) complex was synthesized in the laboratory. The structure and physicochemical properties of the complex were characterized utilizing thermal and spectroscopic (UV-vis, IR and 1H NMR) analysis. The antitumor activity of quercetin-Ge (IV) compound was evaluated by the MTT...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2012-09-01
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| Series: | Main Group Metal Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/mgmc-2012-0026 |
| Summary: | Quercetin-germanium (Ge) (IV) complex was synthesized in the laboratory. The structure and physicochemical properties of the complex were characterized utilizing thermal and spectroscopic (UV-vis, IR and 1H NMR) analysis. The antitumor activity of quercetin-Ge (IV) compound was evaluated by the MTT method. The complex was subjected to biological tests in vitro using four tumor cell lines (PC-3, Hela, EC9706 and SPC-A-1). The quercetin-Ge (IV) complex showed significant cytotoxicity against four tumor cell lines. |
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| ISSN: | 0792-1241 2191-0219 |