Pluronic L81 enhances triacylglycerol accumulation in the cytosol and inhibits chylomicron secretion

Pluronic L81 enhances triacylglycerol accumulation in the cytosol and inhibits chylomicron secretion

Pluronic L81 (PL81) inhibits fat absorption, and other Pluronic copolymers help overcome drug resistance in cancer cells. To understand how PL81 acts, we synthesized a radiolabeled analog, [14C]PL81, and showed that it was structurally similar to PL81 based on 1H NMR as well as mass spectrometric an...

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Bibliographic Details
Main Authors:	Sumbul Fatma, Reuven Yakubov, Kamran Anwar, M. Mahmood Hussain
Format:	Article
Language:	English
Published:	Elsevier 2006-11-01
Series:	Journal of Lipid Research
Subjects:	apolipoprotein B microsomal triglyceride transfer protein lipoproteins phospholipids enterocytes
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520433784

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