Effects of silymarin on neuropathic pain and formalin-induced nociception in mice

Effects of silymarin on neuropathic pain and formalin-induced nociception in mice

Objective(s):Based on the previous reports, silymarin can suppress nitric oxide, prostaglandin E2 (PGE2), leukotrienes, cytokines production, and neutrophils infiltration. Regarding the fact that inflammation plays an important role in neuropathic and formalin-induced pain, it was assumed that silym...

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Bibliographic Details
Main Authors: Faezeh Vahdati Hassani, Ramin Rezaee, Hasan Sazegara, Mahmoud Hashemzaei, Kobra Shirani, Gholamreza Karimi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-07-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Silymarin
Formalin test
Sciatic nerve ligation
Inflammatory pain
Online Access:http://ijbms.mums.ac.ir/pdf_4656_9111d2bc5b4a27bc5937fdfbaa8dd434.html

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