Combining single-cell transcriptomics and CellTagging to identify differentiation trajectories of human adipose-derived mesenchymal stem cells

Combining single-cell transcriptomics and CellTagging to identify differentiation trajectories of human adipose-derived mesenchymal stem cells

Abstract Background Mesenchymal stromal cells (MSCs) have attracted great attention in the application of cell-based therapy because of their pluripotent differentiation and immunomodulatory ability. Due to the limited number of MSCs isolated from donor tissues, a large number of MSCs need to be exp...

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Bibliographic Details
Main Authors: Kai Lin, Yanlei Yang, Yinghao Cao, Junbo Liang, Jun Qian, Xiaoyue Wang, Qin Han
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Stem Cell Research & Therapy
Subjects:
MSCs
Heterogeneity
Single-cell RNA-seq
CellTagging
Osteogenic differentiation
Online Access:https://doi.org/10.1186/s13287-023-03237-3

Internet

https://doi.org/10.1186/s13287-023-03237-3

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