Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report

A 52-year-old woman presented with repeating episodes of pneumonia which spontaneously resolved after hospitalization. Hypersensitivity pneumonitis was suspected, but the causative antigen was not determined whether the parakeets she kept or the humidifier she owned was causative exposure. To identi...

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Main Authors: Takumi Murakami, Yuki Iijima, Takahiro Ando, Masaru Ejima, Tsuyoshi Shirai, Haruhiko Furusawa, Tsukasa Okamoto, Tomoya Tateishi, Meiyo Tamaoka, Yasunari Miyazaki
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007122000612
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author Takumi Murakami
Yuki Iijima
Takahiro Ando
Masaru Ejima
Tsuyoshi Shirai
Haruhiko Furusawa
Tsukasa Okamoto
Tomoya Tateishi
Meiyo Tamaoka
Yasunari Miyazaki
author_facet Takumi Murakami
Yuki Iijima
Takahiro Ando
Masaru Ejima
Tsuyoshi Shirai
Haruhiko Furusawa
Tsukasa Okamoto
Tomoya Tateishi
Meiyo Tamaoka
Yasunari Miyazaki
author_sort Takumi Murakami
collection DOAJ
description A 52-year-old woman presented with repeating episodes of pneumonia which spontaneously resolved after hospitalization. Hypersensitivity pneumonitis was suspected, but the causative antigen was not determined whether the parakeets she kept or the humidifier she owned was causative exposure. To identify which exposure is culprit, individual provocation test to a responsible environment was sequentially conducted. First, a home-returning provocation test to the parakeet was negative. Contrarily, the humidifier provocation test to her own humidifier was positive for symptoms, radiological changes, and inflammatory responses in blood test. Finally, she was diagnosed as having humidifier lung. When several antigens are suspected to be the causative agents for hypersensitivity pneumonitis, a step-by-step provocation tests is useful.
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spelling doaj.art-1eb0adde8a8647b6b52591a45461f68e2022-12-22T00:31:13ZengElsevierRespiratory Medicine Case Reports2213-00712022-01-0137101639Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case reportTakumi Murakami0Yuki Iijima1Takahiro Ando2Masaru Ejima3Tsuyoshi Shirai4Haruhiko Furusawa5Tsukasa Okamoto6Tomoya Tateishi7Meiyo Tamaoka8Yasunari Miyazaki9Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanCorresponding author. Department of Respiratory Medicine Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.; Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanA 52-year-old woman presented with repeating episodes of pneumonia which spontaneously resolved after hospitalization. Hypersensitivity pneumonitis was suspected, but the causative antigen was not determined whether the parakeets she kept or the humidifier she owned was causative exposure. To identify which exposure is culprit, individual provocation test to a responsible environment was sequentially conducted. First, a home-returning provocation test to the parakeet was negative. Contrarily, the humidifier provocation test to her own humidifier was positive for symptoms, radiological changes, and inflammatory responses in blood test. Finally, she was diagnosed as having humidifier lung. When several antigens are suspected to be the causative agents for hypersensitivity pneumonitis, a step-by-step provocation tests is useful.http://www.sciencedirect.com/science/article/pii/S2213007122000612Humidifier lungProvocation testHypersensitivity pneumonitis
spellingShingle Takumi Murakami
Yuki Iijima
Takahiro Ando
Masaru Ejima
Tsuyoshi Shirai
Haruhiko Furusawa
Tsukasa Okamoto
Tomoya Tateishi
Meiyo Tamaoka
Yasunari Miyazaki
Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report
Respiratory Medicine Case Reports
Humidifier lung
Provocation test
Hypersensitivity pneumonitis
title Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report
title_full Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report
title_fullStr Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report
title_full_unstemmed Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report
title_short Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report
title_sort successful diagnosis of humidifier lung by individual provocation test to a responsible environment a case report
topic Humidifier lung
Provocation test
Hypersensitivity pneumonitis
url http://www.sciencedirect.com/science/article/pii/S2213007122000612
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