Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report
A 52-year-old woman presented with repeating episodes of pneumonia which spontaneously resolved after hospitalization. Hypersensitivity pneumonitis was suspected, but the causative antigen was not determined whether the parakeets she kept or the humidifier she owned was causative exposure. To identi...
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Format: | Article |
Language: | English |
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Elsevier
2022-01-01
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Series: | Respiratory Medicine Case Reports |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007122000612 |
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author | Takumi Murakami Yuki Iijima Takahiro Ando Masaru Ejima Tsuyoshi Shirai Haruhiko Furusawa Tsukasa Okamoto Tomoya Tateishi Meiyo Tamaoka Yasunari Miyazaki |
author_facet | Takumi Murakami Yuki Iijima Takahiro Ando Masaru Ejima Tsuyoshi Shirai Haruhiko Furusawa Tsukasa Okamoto Tomoya Tateishi Meiyo Tamaoka Yasunari Miyazaki |
author_sort | Takumi Murakami |
collection | DOAJ |
description | A 52-year-old woman presented with repeating episodes of pneumonia which spontaneously resolved after hospitalization. Hypersensitivity pneumonitis was suspected, but the causative antigen was not determined whether the parakeets she kept or the humidifier she owned was causative exposure. To identify which exposure is culprit, individual provocation test to a responsible environment was sequentially conducted. First, a home-returning provocation test to the parakeet was negative. Contrarily, the humidifier provocation test to her own humidifier was positive for symptoms, radiological changes, and inflammatory responses in blood test. Finally, she was diagnosed as having humidifier lung. When several antigens are suspected to be the causative agents for hypersensitivity pneumonitis, a step-by-step provocation tests is useful. |
first_indexed | 2024-12-12T08:27:28Z |
format | Article |
id | doaj.art-1eb0adde8a8647b6b52591a45461f68e |
institution | Directory Open Access Journal |
issn | 2213-0071 |
language | English |
last_indexed | 2024-12-12T08:27:28Z |
publishDate | 2022-01-01 |
publisher | Elsevier |
record_format | Article |
series | Respiratory Medicine Case Reports |
spelling | doaj.art-1eb0adde8a8647b6b52591a45461f68e2022-12-22T00:31:13ZengElsevierRespiratory Medicine Case Reports2213-00712022-01-0137101639Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case reportTakumi Murakami0Yuki Iijima1Takahiro Ando2Masaru Ejima3Tsuyoshi Shirai4Haruhiko Furusawa5Tsukasa Okamoto6Tomoya Tateishi7Meiyo Tamaoka8Yasunari Miyazaki9Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanCorresponding author. Department of Respiratory Medicine Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.; Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanDepartment of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, JapanA 52-year-old woman presented with repeating episodes of pneumonia which spontaneously resolved after hospitalization. Hypersensitivity pneumonitis was suspected, but the causative antigen was not determined whether the parakeets she kept or the humidifier she owned was causative exposure. To identify which exposure is culprit, individual provocation test to a responsible environment was sequentially conducted. First, a home-returning provocation test to the parakeet was negative. Contrarily, the humidifier provocation test to her own humidifier was positive for symptoms, radiological changes, and inflammatory responses in blood test. Finally, she was diagnosed as having humidifier lung. When several antigens are suspected to be the causative agents for hypersensitivity pneumonitis, a step-by-step provocation tests is useful.http://www.sciencedirect.com/science/article/pii/S2213007122000612Humidifier lungProvocation testHypersensitivity pneumonitis |
spellingShingle | Takumi Murakami Yuki Iijima Takahiro Ando Masaru Ejima Tsuyoshi Shirai Haruhiko Furusawa Tsukasa Okamoto Tomoya Tateishi Meiyo Tamaoka Yasunari Miyazaki Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report Respiratory Medicine Case Reports Humidifier lung Provocation test Hypersensitivity pneumonitis |
title | Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report |
title_full | Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report |
title_fullStr | Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report |
title_full_unstemmed | Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report |
title_short | Successful diagnosis of humidifier lung by individual provocation test to a responsible environment, a case report |
title_sort | successful diagnosis of humidifier lung by individual provocation test to a responsible environment a case report |
topic | Humidifier lung Provocation test Hypersensitivity pneumonitis |
url | http://www.sciencedirect.com/science/article/pii/S2213007122000612 |
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