The role of inflammatory mediators and matrix metalloproteinases (MMPs) in the progression of osteoarthritis

Osteoarthritis (OA) is a chronic musculoskeletal disorder characterized by an imbalance between (synthesis) and catabolism (degradation) in altered homeostasis of articular cartilage mediated primarily by the innate immune system. OA degenerates the joints resulting in synovial hyperplasia, degradat...

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Bibliographic Details
Main Authors: Anwesha Mukherjee, Bodhisatwa Das
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biomaterials and Biosystems
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666534424000035