Global Perspective on the Management of Peyronie's Disease

IntroductionPeyronie's disease is the disease that results in an alteration in the curvature of the penis, which can lead to a shortening of length, pain in erection, or difficulties in penetration, thus leading the patient to psychological alterations due to loss of functionality such as aesth...

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Main Authors: Gabriel Veber Moisés da Silva, Francisco Javier Dávila, Tiago Elias Rosito, Francisco E. Martins
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Reproductive Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/frph.2022.863844/full
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author Gabriel Veber Moisés da Silva
Francisco Javier Dávila
Tiago Elias Rosito
Francisco E. Martins
author_facet Gabriel Veber Moisés da Silva
Francisco Javier Dávila
Tiago Elias Rosito
Francisco E. Martins
author_sort Gabriel Veber Moisés da Silva
collection DOAJ
description IntroductionPeyronie's disease is the disease that results in an alteration in the curvature of the penis, which can lead to a shortening of length, pain in erection, or difficulties in penetration, thus leading the patient to psychological alterations due to loss of functionality such as aesthetic alteration. That is why there are several studies to define the best form of treatment, which currently continues to be the first choice surgical treatment.ObjectiveWe present the most recommended therapies for Peyronie's disease and suggest an algorithm as a guide to direct therapy.MethodsWe used the PubMed platform to review the literature related to Peyronie's disease. Various editorials were reviewed as well as original articles and reviews focusing on the various treatments as well as their indications and results.ResultsPeyronie's disease in which conservative or drug treatment does not have a response, surgical treatment with corporoplasty, penile prosthesis implantation or both may be indicated. Corporoplasty refers to both the plication of the tunica albuginea as well as the incision of the tunica with the placement of a graft. An accurate history should always be carried out to identify erectile dysfunction as well as to be able to guide you on the repercussions of the treatment. If refractory erectile dysfunction is present, placement of a penile prosthesis with or without further adjunctive straightening maneuvers is recommended. We reviewed the indications, advantages, disadvantages, and results of the available techniques, and proposed a surgical treatment algorithm.ConclusionPenile shortening procedures are usually indicated in curvatures <60°, in penises with adequate length. Partial excision/incision and grafting are indicated for curvatures >60°, hourglass or hinge deformities, and short penises, if the patient's erectile function is adequate. The presence of “borderline” erectile function and/or ventral curvature tilts the choice toward shortening procedures, and refractory erectile dysfunction is an indication for penile prosthesis placement. An accurate risk/benefit assessment of the individual patient as well as meticulous patient counseling are critically important.
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spelling doaj.art-1eb3442b69cf422cbd0ab5118a5cf25e2022-12-22T02:31:50ZengFrontiers Media S.A.Frontiers in Reproductive Health2673-31532022-06-01410.3389/frph.2022.863844863844Global Perspective on the Management of Peyronie's DiseaseGabriel Veber Moisés da Silva0Francisco Javier Dávila1Tiago Elias Rosito2Francisco E. Martins3Department of Urology, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, BrazilDepartment of Urology, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, BrazilDepartment of Urology, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, BrazilDepartment of Urology, University of Lisbon, School of Medicine, Centro Hospitalar Universitario Lisboa Norte (CHULN), Lisbon, PortugalIntroductionPeyronie's disease is the disease that results in an alteration in the curvature of the penis, which can lead to a shortening of length, pain in erection, or difficulties in penetration, thus leading the patient to psychological alterations due to loss of functionality such as aesthetic alteration. That is why there are several studies to define the best form of treatment, which currently continues to be the first choice surgical treatment.ObjectiveWe present the most recommended therapies for Peyronie's disease and suggest an algorithm as a guide to direct therapy.MethodsWe used the PubMed platform to review the literature related to Peyronie's disease. Various editorials were reviewed as well as original articles and reviews focusing on the various treatments as well as their indications and results.ResultsPeyronie's disease in which conservative or drug treatment does not have a response, surgical treatment with corporoplasty, penile prosthesis implantation or both may be indicated. Corporoplasty refers to both the plication of the tunica albuginea as well as the incision of the tunica with the placement of a graft. An accurate history should always be carried out to identify erectile dysfunction as well as to be able to guide you on the repercussions of the treatment. If refractory erectile dysfunction is present, placement of a penile prosthesis with or without further adjunctive straightening maneuvers is recommended. We reviewed the indications, advantages, disadvantages, and results of the available techniques, and proposed a surgical treatment algorithm.ConclusionPenile shortening procedures are usually indicated in curvatures <60°, in penises with adequate length. Partial excision/incision and grafting are indicated for curvatures >60°, hourglass or hinge deformities, and short penises, if the patient's erectile function is adequate. The presence of “borderline” erectile function and/or ventral curvature tilts the choice toward shortening procedures, and refractory erectile dysfunction is an indication for penile prosthesis placement. An accurate risk/benefit assessment of the individual patient as well as meticulous patient counseling are critically important.https://www.frontiersin.org/articles/10.3389/frph.2022.863844/fullgraftingpenilecurvaturedeformityplaqueprosthesis
spellingShingle Gabriel Veber Moisés da Silva
Francisco Javier Dávila
Tiago Elias Rosito
Francisco E. Martins
Global Perspective on the Management of Peyronie's Disease
Frontiers in Reproductive Health
grafting
penile
curvature
deformity
plaque
prosthesis
title Global Perspective on the Management of Peyronie's Disease
title_full Global Perspective on the Management of Peyronie's Disease
title_fullStr Global Perspective on the Management of Peyronie's Disease
title_full_unstemmed Global Perspective on the Management of Peyronie's Disease
title_short Global Perspective on the Management of Peyronie's Disease
title_sort global perspective on the management of peyronie s disease
topic grafting
penile
curvature
deformity
plaque
prosthesis
url https://www.frontiersin.org/articles/10.3389/frph.2022.863844/full
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