The Phospholipase A2 Superfamily: Structure, Isozymes, Catalysis, Physiologic and Pathologic Roles

The Phospholipase A2 Superfamily: Structure, Isozymes, Catalysis, Physiologic and Pathologic Roles

The phospholipase A2 (PLA2) superfamily of phospholipase enzymes hydrolyzes the ester bond at the sn-2 position of the phospholipids, generating a free fatty acid and a lysophospholipid. The PLA2s are amphiphilic in nature and work only at the water/lipid interface, acting on phospholipid assemblies...

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Bibliographic Details
Main Authors:	Shibbir Ahmed Khan, Marc A. Ilies
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	International Journal of Molecular Sciences
Subjects:	phospholipase A2 structure isozyme kinetics catalysis activation mechanism
Online Access:	https://www.mdpi.com/1422-0067/24/2/1353

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