The miR-668 binding site variant rs1046322 on WFS1 is associated with obesity in Southeast Asians

The miR-668 binding site variant rs1046322 on WFS1 is associated with obesity in Southeast Asians

The Wolfram syndrome 1 gene (WFS1) is the main causative locus for Wolfram syndrome, an inherited condition characterized by childhood-onset diabetes mellitus, optic atrophy, and deafness. Global genome-wide association studies have listed at least 19 WFS1 variants that are associated with type 2 di...

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Bibliographic Details
Main Authors: Maha M. Hammad, Mohamed Abu-Farha, Prashantha Hebbar, Emil Anoop, Betty Chandy, Motasem Melhem, Arshad Channanath, Fahd Al-Mulla, Thangavel Alphonse Thanaraj, Jehad Abubaker
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
WFS1
ethnicity
obesity
triglycerides
polymorphism
waist circumference
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1185956/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1185956/full

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