Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019

The coronavirus disease 2019 (COVID-19) pandemic started in Wuhan, Hubei Province, China, in December 2019, and by 24 April 2020, it had affected >2.73 million people in 185 countries and caused >192,000 deaths. Despite diverse societal measures to reduce transmission of the severe acute respi...

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Main Authors: Ernest Spitzer, Ben Ren, Jasper J Brugts, Joost Daemen, Eugene McFadden, Jan GP Tijssen, Nicolas M Van Mieghem
Format: Article
Language:English
Published: Radcliffe Medical Media 2020-05-01
Series:Cardiac Failure Review
Online Access:https://www.cfrjournal.com/articles/cardiovascular-clinical-trials-Coronavirus-COVID-19-pandemic
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author Ernest Spitzer
Ben Ren
Jasper J Brugts
Joost Daemen
Eugene McFadden
Jan GP Tijssen
Nicolas M Van Mieghem
author_facet Ernest Spitzer
Ben Ren
Jasper J Brugts
Joost Daemen
Eugene McFadden
Jan GP Tijssen
Nicolas M Van Mieghem
author_sort Ernest Spitzer
collection DOAJ
description The coronavirus disease 2019 (COVID-19) pandemic started in Wuhan, Hubei Province, China, in December 2019, and by 24 April 2020, it had affected >2.73 million people in 185 countries and caused >192,000 deaths. Despite diverse societal measures to reduce transmission of the severe acute respiratory syndrome coronavirus 2, such as implementing social distancing, quarantine, curfews and total lockdowns, its control remains challenging. Healthcare practitioners are at the frontline of defence against the virus, with increasing institutional and governmental supports. Nevertheless, new or ongoing clinical trials, not related to the disease itself, remain important for the development of new therapies, and require interactions among patients, clinicians and research personnel, which is challenging, given isolation measures. In this article, the authors summarise the acute effects and consequences of the COVID-19 pandemic on current cardiovascular trials.
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spelling doaj.art-1ebdf01778c24f519e49f3107d6ea9f32024-04-20T16:01:40ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592020-05-01610.15420/cfr.2020.07Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019Ernest Spitzer0Ben Ren1Jasper J Brugts2Joost Daemen3Eugene McFadden4Jan GP Tijssen5Nicolas M Van Mieghem6Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands; Cardialysis, Clinical Trial Management and Core Laboratories, Rotterdam, the NetherlandsDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands; Cardialysis, Clinical Trial Management and Core Laboratories, Rotterdam, the NetherlandsDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands; Cardialysis, Clinical Trial Management and Core Laboratories, Rotterdam, the NetherlandsDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands; Cardialysis, Clinical Trial Management and Core Laboratories, Rotterdam, the NetherlandsCardialysis, Clinical Trial Management and Core Laboratories, Rotterdam, the Netherlands; Department of Cardiology, Cork University Hospital, Cork, IrelandCardialysis, Clinical Trial Management and Core Laboratories, Rotterdam, the Netherlands; Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the NetherlandsDepartment of Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands; Cardialysis, Clinical Trial Management and Core Laboratories, Rotterdam, the NetherlandsThe coronavirus disease 2019 (COVID-19) pandemic started in Wuhan, Hubei Province, China, in December 2019, and by 24 April 2020, it had affected >2.73 million people in 185 countries and caused >192,000 deaths. Despite diverse societal measures to reduce transmission of the severe acute respiratory syndrome coronavirus 2, such as implementing social distancing, quarantine, curfews and total lockdowns, its control remains challenging. Healthcare practitioners are at the frontline of defence against the virus, with increasing institutional and governmental supports. Nevertheless, new or ongoing clinical trials, not related to the disease itself, remain important for the development of new therapies, and require interactions among patients, clinicians and research personnel, which is challenging, given isolation measures. In this article, the authors summarise the acute effects and consequences of the COVID-19 pandemic on current cardiovascular trials.https://www.cfrjournal.com/articles/cardiovascular-clinical-trials-Coronavirus-COVID-19-pandemic
spellingShingle Ernest Spitzer
Ben Ren
Jasper J Brugts
Joost Daemen
Eugene McFadden
Jan GP Tijssen
Nicolas M Van Mieghem
Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019
Cardiac Failure Review
title Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019
title_full Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019
title_fullStr Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019
title_full_unstemmed Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019
title_short Cardiovascular Clinical Trials in a Pandemic: Immediate Implications of Coronavirus Disease 2019
title_sort cardiovascular clinical trials in a pandemic immediate implications of coronavirus disease 2019
url https://www.cfrjournal.com/articles/cardiovascular-clinical-trials-Coronavirus-COVID-19-pandemic
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