Comparison of below‐knee and above‐knee amputations with demographic, comorbidity, and haematological parameters in patients who died

Abstract Background This study aimed to establish mortality predictive parameters with a higher contribution to mortality by comparing the demographic data, comorbid factors, and haematological values of patients who underwent below‐knee and above‐knee amputation and had died during the follow‐up pe...

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Main Authors: Cafer Özgür Hançerli, Necati Doğan
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Foot and Ankle Research
Subjects:
Online Access:https://doi.org/10.1186/s13047-023-00635-x
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author Cafer Özgür Hançerli
Necati Doğan
author_facet Cafer Özgür Hançerli
Necati Doğan
author_sort Cafer Özgür Hançerli
collection DOAJ
description Abstract Background This study aimed to establish mortality predictive parameters with a higher contribution to mortality by comparing the demographic data, comorbid factors, and haematological values of patients who underwent below‐knee and above‐knee amputation and had died during the follow‐up period. Materials and methods Between March 2014 and January 2022, 122 patients in a single centre who developed foot gangrene due to chronic diabetes and underwent below‐knee or above‐knee amputation were evaluated retrospectively. Patients who died of natural causes during the post‐operative period were included in the study. Those who were amputated below the knee were assigned to Group 1, and those who were amputated above the knee were assigned to Group 2. The patients' age, gender, side of amputation, comorbid diseases, American Society of Anaesthesiologists (ASA) score, Charlson comorbidity index (CCI), death time, and haematological values at the time of first admission were compared between the two groups and statistical analyses were performed. Results Group 1 (n = 50) and Group 2 (n = 37) had similar distributions in terms of age, gender, side of operation, number of comorbidities, and CCI (p > 0.05). Group 2's mean ASA score and c‐reactive protein (CRP) levels were statistically higher than those of Group 1 (p < 0.05). Death time, albumin value, and HbA1c levels were statistically lower in Group 2 than in Group 1 (p < 0.05). There were no significant differences between the groups in haemogram, white blood cells (WBC), lymphocytes, neutrophils, creatinine, and Na values at the time of first admission (p > 0.05). Conclusion A high ASA score, low albumin value, and high CRP value were significant predictors of high mortality. Creatinine levels and HbA1c values were quite ineffective in predicting mortality. Level of evidence Level 3, retrospective comparative study.
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spelling doaj.art-1ebff31e98a544c79a479adc4244bae82024-02-07T15:05:47ZengWileyJournal of Foot and Ankle Research1757-11462023-01-01161n/an/a10.1186/s13047-023-00635-xComparison of below‐knee and above‐knee amputations with demographic, comorbidity, and haematological parameters in patients who diedCafer Özgür Hançerli0Necati Doğan1Department of Orthopaedics and TraumatologyUniversity of Health SciencesKanuni Sultan Süleyman Training and Research HospitalIstanbulTurkeyDepartment of Orthopaedics and TraumatologyBaşaksehir Çam and Sakura City Training and Research HospitalBasaksehir Olimpiyat Bulvarı Yolu34480Basaksehir, IstanbulTurkeyAbstract Background This study aimed to establish mortality predictive parameters with a higher contribution to mortality by comparing the demographic data, comorbid factors, and haematological values of patients who underwent below‐knee and above‐knee amputation and had died during the follow‐up period. Materials and methods Between March 2014 and January 2022, 122 patients in a single centre who developed foot gangrene due to chronic diabetes and underwent below‐knee or above‐knee amputation were evaluated retrospectively. Patients who died of natural causes during the post‐operative period were included in the study. Those who were amputated below the knee were assigned to Group 1, and those who were amputated above the knee were assigned to Group 2. The patients' age, gender, side of amputation, comorbid diseases, American Society of Anaesthesiologists (ASA) score, Charlson comorbidity index (CCI), death time, and haematological values at the time of first admission were compared between the two groups and statistical analyses were performed. Results Group 1 (n = 50) and Group 2 (n = 37) had similar distributions in terms of age, gender, side of operation, number of comorbidities, and CCI (p > 0.05). Group 2's mean ASA score and c‐reactive protein (CRP) levels were statistically higher than those of Group 1 (p < 0.05). Death time, albumin value, and HbA1c levels were statistically lower in Group 2 than in Group 1 (p < 0.05). There were no significant differences between the groups in haemogram, white blood cells (WBC), lymphocytes, neutrophils, creatinine, and Na values at the time of first admission (p > 0.05). Conclusion A high ASA score, low albumin value, and high CRP value were significant predictors of high mortality. Creatinine levels and HbA1c values were quite ineffective in predicting mortality. Level of evidence Level 3, retrospective comparative study.https://doi.org/10.1186/s13047-023-00635-xAbove‐knee amputationBelow‐knee amputationDiabetic footMortality predictive parameters
spellingShingle Cafer Özgür Hançerli
Necati Doğan
Comparison of below‐knee and above‐knee amputations with demographic, comorbidity, and haematological parameters in patients who died
Journal of Foot and Ankle Research
Above‐knee amputation
Below‐knee amputation
Diabetic foot
Mortality predictive parameters
title Comparison of below‐knee and above‐knee amputations with demographic, comorbidity, and haematological parameters in patients who died
title_full Comparison of below‐knee and above‐knee amputations with demographic, comorbidity, and haematological parameters in patients who died
title_fullStr Comparison of below‐knee and above‐knee amputations with demographic, comorbidity, and haematological parameters in patients who died
title_full_unstemmed Comparison of below‐knee and above‐knee amputations with demographic, comorbidity, and haematological parameters in patients who died
title_short Comparison of below‐knee and above‐knee amputations with demographic, comorbidity, and haematological parameters in patients who died
title_sort comparison of below knee and above knee amputations with demographic comorbidity and haematological parameters in patients who died
topic Above‐knee amputation
Below‐knee amputation
Diabetic foot
Mortality predictive parameters
url https://doi.org/10.1186/s13047-023-00635-x
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