Analysis and modeling of cancer drug responses using cell cycle phase-specific rate effects

Abstract Identifying effective therapeutic treatment strategies is a major challenge to improving outcomes for patients with breast cancer. To gain a comprehensive understanding of how clinically relevant anti-cancer agents modulate cell cycle progression, here we use genetically engineered breast c...

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Bibliographic Details
Main Authors: Sean M. Gross, Farnaz Mohammadi, Crystal Sanchez-Aguila, Paulina J. Zhan, Tiera A. Liby, Mark A. Dane, Aaron S. Meyer, Laura M. Heiser
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39122-z

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