ER-Localized PIN Carriers: Regulators of Intracellular Auxin Homeostasis
The proper distribution of the hormone auxin is essential for plant development. It is channeled by auxin efflux carriers of the PIN family, typically asymmetrically located on the plasma membrane (PM). Several studies demonstrated that some PIN transporters are also located at the endoplasmic retic...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-11-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/9/11/1527 |
| _version_ | 1797548380416638976 |
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| author | Nayyer Abdollahi Sisi Kamil Růžička |
| author_facet | Nayyer Abdollahi Sisi Kamil Růžička |
| author_sort | Nayyer Abdollahi Sisi |
| collection | DOAJ |
| description | The proper distribution of the hormone auxin is essential for plant development. It is channeled by auxin efflux carriers of the PIN family, typically asymmetrically located on the plasma membrane (PM). Several studies demonstrated that some PIN transporters are also located at the endoplasmic reticulum (ER). From the PM-PINs, they differ in a shorter internal hydrophilic loop, which carries the most important structural features required for their subcellular localization, but their biological role is otherwise relatively poorly known. We discuss how ER-PINs take part in maintaining intracellular auxin homeostasis, possibly by modulating the internal levels of IAA; it seems that the exact identity of the metabolites downstream of ER-PINs is not entirely clear as well. We further review the current knowledge about their predicted structure, evolution and localization. Finally, we also summarize their role in plant development. |
| first_indexed | 2024-03-10T14:58:33Z |
| format | Article |
| id | doaj.art-1ec1ca031b94425392698b1bdd9f5801 |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-10T14:58:33Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-1ec1ca031b94425392698b1bdd9f58012023-11-20T20:22:04ZengMDPI AGPlants2223-77472020-11-01911152710.3390/plants9111527ER-Localized PIN Carriers: Regulators of Intracellular Auxin HomeostasisNayyer Abdollahi Sisi0Kamil Růžička1Laboratory of Hormonal Regulations in Plants, Institute of Experimental Botany, Czech Academy of Sciences, 16502 Prague, Czech RepublicLaboratory of Hormonal Regulations in Plants, Institute of Experimental Botany, Czech Academy of Sciences, 16502 Prague, Czech RepublicThe proper distribution of the hormone auxin is essential for plant development. It is channeled by auxin efflux carriers of the PIN family, typically asymmetrically located on the plasma membrane (PM). Several studies demonstrated that some PIN transporters are also located at the endoplasmic reticulum (ER). From the PM-PINs, they differ in a shorter internal hydrophilic loop, which carries the most important structural features required for their subcellular localization, but their biological role is otherwise relatively poorly known. We discuss how ER-PINs take part in maintaining intracellular auxin homeostasis, possibly by modulating the internal levels of IAA; it seems that the exact identity of the metabolites downstream of ER-PINs is not entirely clear as well. We further review the current knowledge about their predicted structure, evolution and localization. Finally, we also summarize their role in plant development.https://www.mdpi.com/2223-7747/9/11/1527ER-PINsPIN proteinsPIN5PIN8auxin transportauxin metabolism |
| spellingShingle | Nayyer Abdollahi Sisi Kamil Růžička ER-Localized PIN Carriers: Regulators of Intracellular Auxin Homeostasis Plants ER-PINs PIN proteins PIN5 PIN8 auxin transport auxin metabolism |
| title | ER-Localized PIN Carriers: Regulators of Intracellular Auxin Homeostasis |
| title_full | ER-Localized PIN Carriers: Regulators of Intracellular Auxin Homeostasis |
| title_fullStr | ER-Localized PIN Carriers: Regulators of Intracellular Auxin Homeostasis |
| title_full_unstemmed | ER-Localized PIN Carriers: Regulators of Intracellular Auxin Homeostasis |
| title_short | ER-Localized PIN Carriers: Regulators of Intracellular Auxin Homeostasis |
| title_sort | er localized pin carriers regulators of intracellular auxin homeostasis |
| topic | ER-PINs PIN proteins PIN5 PIN8 auxin transport auxin metabolism |
| url | https://www.mdpi.com/2223-7747/9/11/1527 |
| work_keys_str_mv | AT nayyerabdollahisisi erlocalizedpincarriersregulatorsofintracellularauxinhomeostasis AT kamilruzicka erlocalizedpincarriersregulatorsofintracellularauxinhomeostasis |