Cortisol inhibits mTOR signaling in avascular necrosis of the femoral head

Cortisol inhibits mTOR signaling in avascular necrosis of the femoral head

Abstract Background ANFH is a major health problem, to which long lasting and definitive treatments are lacking. The aim of this study is to study RNA alterations attributed to cortisol-induced ANFH. Methods Rat models were stratified into three groups: in vitro group (n = 20) for molecular biologic...

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Bibliographic Details
Main Authors: Yun Liao, Rui Su, Ping Zhang, Bo Yuan, Ling Li
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Avascular necrosis of the femoral head
Cortisol
mTOR
HIF
Online Access:http://link.springer.com/article/10.1186/s13018-017-0656-2

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