Mitochondrial dysregulation and muscle disuse atrophy [version 1; peer review: 2 approved]
It is well established that mitochondria play a critical role in the metabolic and physiological adaptation of skeletal muscle to enhanced contractile activity. Several redox-sensitive signaling pathways such as PGC-1α, AMPK, IGF/Akt/mTOR, SIRT, NFκB, and FoxO are involved with extensive crosstalk t...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2019-09-01
|
| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-1621/v1 |