Analysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems.

Analysis of the molecular networks in androgen dependent and independent prostate cancer revealed fragile and robust subsystems.

Androgen ablation therapy is currently the primary treatment for metastatic prostate cancer. Unfortunately, in nearly all cases, androgen ablation fails to permanently arrest cancer progression. As androgens like testosterone are withdrawn, prostate cancer cells lose their androgen sensitivity and b...

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Bibliographic Details
Main Authors: Ryan Tasseff, Satyaprakash Nayak, Saniya Salim, Poorvi Kaushik, Noreen Rizvi, Jeffrey D Varner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2812491?pdf=render

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