Recombinant Alpha-1-Microglobulin (RMC-035) to Prevent Acute Kidney Injury in Cardiac Surgery Patients: Phase 1b Evaluation of Safety and Pharmacokinetics

Recombinant Alpha-1-Microglobulin (RMC-035) to Prevent Acute Kidney Injury in Cardiac Surgery Patients: Phase 1b Evaluation of Safety and Pharmacokinetics

Introduction: Acute kidney injury (AKI) is a common complication in cardiac surgery patients and prevention is needed to improve clinical outcomes. Alpha-1-microglobulin (A1M) is a physiological antioxidant with strong tissue-protective and cell-protective properties that has demonstrated renoprotec...

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Bibliographic Details
Main Authors:	Raphael Weiss, Melanie Meersch, Carola Wempe, Thilo von Groote, Tobias Agervald, Alexander Zarbock
Format:	Article
Language:	English
Published:	Elsevier 2023-05-01
Series:	Kidney International Reports
Subjects:	acute kidney injury alpha-1-microglobulin cardiac surgery inflammation perioperative medicine prevention
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468024923011683

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