Mechanical properties of the premature lung: From tissue deformation under load to mechanosensitivity of alveolar cells
Many preterm infants require mechanical ventilation as life-saving therapy. However, ventilation-induced overpressure can result in lung diseases. Considering the lung as a viscoelastic material, positive pressure inside the lung results in increased hydrostatic pressure and tissue compression. To e...
Main Authors: | Jonas Naumann, Nicklas Koppe, Ulrich H. Thome, Mandy Laube, Mareike Zink |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.964318/full |
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