Microrheological Disorders in Critical Conditions

The review describes the role of a change in the morphofunctional properties of red blood cells in the pathogenesis of severe concomitant injury, sepsis, and acute respiratory distress syndrome. The authors give data on the nonspecific mechanisms responsible for the provision and maintenance of oxyg...

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Main Authors: L. V. Gerasimov, V. V. Moroz, A. A. Isakova
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2010-02-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/510
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author L. V. Gerasimov
V. V. Moroz
A. A. Isakova
author_facet L. V. Gerasimov
V. V. Moroz
A. A. Isakova
author_sort L. V. Gerasimov
collection DOAJ
description The review describes the role of a change in the morphofunctional properties of red blood cells in the pathogenesis of severe concomitant injury, sepsis, and acute respiratory distress syndrome. The authors give data on the nonspecific mechanisms responsible for the provision and maintenance of oxygen transport at the microvascular level. Furthermore, the review summarizes the results of recent studies dealing with the contribution of microrheological disorders to the development of organ dysfunction in sepsis and other critical conditions. Whether microrheological disorders can be corrected is also considered. Key words: critical conditions, erythrocyte deformability, erythrocyte aggregation, perftoran, infusion therapy.
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spelling doaj.art-1ed0ce554cee4960b51655bd5a48b3012023-03-13T09:32:50ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102010-02-016110.15360/1813-9779-2010-1-74510Microrheological Disorders in Critical ConditionsL. V. GerasimovV. V. MorozA. A. IsakovaThe review describes the role of a change in the morphofunctional properties of red blood cells in the pathogenesis of severe concomitant injury, sepsis, and acute respiratory distress syndrome. The authors give data on the nonspecific mechanisms responsible for the provision and maintenance of oxygen transport at the microvascular level. Furthermore, the review summarizes the results of recent studies dealing with the contribution of microrheological disorders to the development of organ dysfunction in sepsis and other critical conditions. Whether microrheological disorders can be corrected is also considered. Key words: critical conditions, erythrocyte deformability, erythrocyte aggregation, perftoran, infusion therapy.https://www.reanimatology.com/rmt/article/view/510
spellingShingle L. V. Gerasimov
V. V. Moroz
A. A. Isakova
Microrheological Disorders in Critical Conditions
Общая реаниматология
title Microrheological Disorders in Critical Conditions
title_full Microrheological Disorders in Critical Conditions
title_fullStr Microrheological Disorders in Critical Conditions
title_full_unstemmed Microrheological Disorders in Critical Conditions
title_short Microrheological Disorders in Critical Conditions
title_sort microrheological disorders in critical conditions
url https://www.reanimatology.com/rmt/article/view/510
work_keys_str_mv AT lvgerasimov microrheologicaldisordersincriticalconditions
AT vvmoroz microrheologicaldisordersincriticalconditions
AT aaisakova microrheologicaldisordersincriticalconditions