Percutaneous ablation techniques for renal cell carcinoma: current status and future trends

Percutaneous ablation is an increasingly applied technique for the treatment of localized renal tumors, especially for elderly or co-morbid patients, where co-morbidities increase the risk of traditional nephrectomy. Ablative techniques are technically suited for the treatment of tumors generally no...

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Main Authors: D. Filippiadis, G. Mauri, P. Marra, G. Charalampopoulos, N. Gennaro, F. De Cobelli
Format: Article
Language:English
Published: Taylor & Francis Group 2019-10-01
Series:International Journal of Hyperthermia
Subjects:
Online Access:http://dx.doi.org/10.1080/02656736.2019.1647352
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author D. Filippiadis
G. Mauri
P. Marra
G. Charalampopoulos
N. Gennaro
F. De Cobelli
author_facet D. Filippiadis
G. Mauri
P. Marra
G. Charalampopoulos
N. Gennaro
F. De Cobelli
author_sort D. Filippiadis
collection DOAJ
description Percutaneous ablation is an increasingly applied technique for the treatment of localized renal tumors, especially for elderly or co-morbid patients, where co-morbidities increase the risk of traditional nephrectomy. Ablative techniques are technically suited for the treatment of tumors generally not exceeding 4 cm, which has been set as general consensus cutoff and is described as the upper threshold of T1a kidney tumors. This threshold cutoff is being challenged, but with still limited evidence. Percutaneous ablation techniques for the treatment of renal cell carcinoma (RCC) include radiofrequency ablation, cryoablation, laser or microwave ablation; the main advantage of all these techniques over surgery is less invasiveness, lower complication rates and better patient tolerability. Currently, international guidelines recommend percutaneous ablation either as intervention for frail patients or as a first line tool, provided that the tumor can be radically ablated. The purpose of this article is to describe the basic concepts of percutaneous ablation in the treatment of RCC. Controversies concerning techniques and products and the need for patient-centered tailored approaches during selection among the different techniques available will be discussed.
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spelling doaj.art-1ed0f610938a416caba61887df28db662022-12-21T17:31:25ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572019-10-01362213010.1080/02656736.2019.16473521647352Percutaneous ablation techniques for renal cell carcinoma: current status and future trendsD. Filippiadis0G. Mauri1P. Marra2G. Charalampopoulos3N. Gennaro4F. De Cobelli5University General Hospital “ATTIKON”, Medical School, National and Kapodistrian University of AthensEuropean Institute of Oncology, IRCCSSan Raffaele Scientific InstituteUniversity General Hospital “ATTIKON”, Medical School, National and Kapodistrian University of AthensEuropean Institute of Oncology, IRCCSSan Raffaele Scientific InstitutePercutaneous ablation is an increasingly applied technique for the treatment of localized renal tumors, especially for elderly or co-morbid patients, where co-morbidities increase the risk of traditional nephrectomy. Ablative techniques are technically suited for the treatment of tumors generally not exceeding 4 cm, which has been set as general consensus cutoff and is described as the upper threshold of T1a kidney tumors. This threshold cutoff is being challenged, but with still limited evidence. Percutaneous ablation techniques for the treatment of renal cell carcinoma (RCC) include radiofrequency ablation, cryoablation, laser or microwave ablation; the main advantage of all these techniques over surgery is less invasiveness, lower complication rates and better patient tolerability. Currently, international guidelines recommend percutaneous ablation either as intervention for frail patients or as a first line tool, provided that the tumor can be radically ablated. The purpose of this article is to describe the basic concepts of percutaneous ablation in the treatment of RCC. Controversies concerning techniques and products and the need for patient-centered tailored approaches during selection among the different techniques available will be discussed.http://dx.doi.org/10.1080/02656736.2019.1647352Imaginglaserradiofrequency/microwavethermal ablationimaging (i.ePETCTMRI)
spellingShingle D. Filippiadis
G. Mauri
P. Marra
G. Charalampopoulos
N. Gennaro
F. De Cobelli
Percutaneous ablation techniques for renal cell carcinoma: current status and future trends
International Journal of Hyperthermia
Imaging
laser
radiofrequency/microwave
thermal ablation
imaging (i.e
PET
CT
MRI)
title Percutaneous ablation techniques for renal cell carcinoma: current status and future trends
title_full Percutaneous ablation techniques for renal cell carcinoma: current status and future trends
title_fullStr Percutaneous ablation techniques for renal cell carcinoma: current status and future trends
title_full_unstemmed Percutaneous ablation techniques for renal cell carcinoma: current status and future trends
title_short Percutaneous ablation techniques for renal cell carcinoma: current status and future trends
title_sort percutaneous ablation techniques for renal cell carcinoma current status and future trends
topic Imaging
laser
radiofrequency/microwave
thermal ablation
imaging (i.e
PET
CT
MRI)
url http://dx.doi.org/10.1080/02656736.2019.1647352
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AT gmauri percutaneousablationtechniquesforrenalcellcarcinomacurrentstatusandfuturetrends
AT pmarra percutaneousablationtechniquesforrenalcellcarcinomacurrentstatusandfuturetrends
AT gcharalampopoulos percutaneousablationtechniquesforrenalcellcarcinomacurrentstatusandfuturetrends
AT ngennaro percutaneousablationtechniquesforrenalcellcarcinomacurrentstatusandfuturetrends
AT fdecobelli percutaneousablationtechniquesforrenalcellcarcinomacurrentstatusandfuturetrends