Higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in South Korea: A nationwide population-based study.
PURPOSE:To investigate the incidence of corneal transplantation and identify rates and risk factors of repeated corneal transplantation in South Korea. METHODS:This is a retrospective population-based cohort study using the Korean National Health Insurance System database. Among the entire South Kor...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2020-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0235233 |
| _version_ | 1818985562358415360 |
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| author | Kyoung Yoon Shin Dong Hui Lim Kyungdo Han Tae-Young Chung |
| author_facet | Kyoung Yoon Shin Dong Hui Lim Kyungdo Han Tae-Young Chung |
| author_sort | Kyoung Yoon Shin |
| collection | DOAJ |
| description | PURPOSE:To investigate the incidence of corneal transplantation and identify rates and risk factors of repeated corneal transplantation in South Korea. METHODS:This is a retrospective population-based cohort study using the Korean National Health Insurance System database. Among the entire South Korean population (N = 51,827,813), we included those who underwent corneal transplantation more than once between January 2006 and December 2016, and analyzed the annual incidence of keratoplasty. The person-year incidence of repeated keratoplasty after the first operation was calculated according to risk factors including age group, sex, income level, surgical method, surgical etiology, and presence of major systemic diseases. Cox regression analysis was employed to evaluate the hazard ratios of those risk factors on repeated keratoplasty. RESULTS:A total of 9,452 cases of corneal transplantation occurred from January 2006 to December 2016. The average annual incidence of corneal transplantations was 1.694 per 100,000. The proportion of penetrating keratoplasty steadily decreased from 92.22% in 2006 to 77.81% in 2016. The average incidence of repeated keratoplasty among those who underwent corneal transplantation at least once was 43.24 per 1,000 person-years. Males had a greater incidence of repeated keratoplasty compared to females (males: 47.66 per 1,000, females: 36.04 per 1,000). The age group from 20 to 39 years demonstrated the lowest incidence of repeated keratoplasty at 24.94 per 1,000. Keratoconus had the lowest incidence of repeated keratoplasty (22.82 per 1,000). CONCLUSION:This study may provide a better understanding of corneal diseases, help predict disease burden, and plan health care systems accordingly in South Korea. |
| first_indexed | 2024-12-20T18:36:52Z |
| format | Article |
| id | doaj.art-1edab5dd4113417591a09a9c2d3ef051 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T18:36:52Z |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-1edab5dd4113417591a09a9c2d3ef0512022-12-21T19:29:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01157e023523310.1371/journal.pone.0235233Higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in South Korea: A nationwide population-based study.Kyoung Yoon ShinDong Hui LimKyungdo HanTae-Young ChungPURPOSE:To investigate the incidence of corneal transplantation and identify rates and risk factors of repeated corneal transplantation in South Korea. METHODS:This is a retrospective population-based cohort study using the Korean National Health Insurance System database. Among the entire South Korean population (N = 51,827,813), we included those who underwent corneal transplantation more than once between January 2006 and December 2016, and analyzed the annual incidence of keratoplasty. The person-year incidence of repeated keratoplasty after the first operation was calculated according to risk factors including age group, sex, income level, surgical method, surgical etiology, and presence of major systemic diseases. Cox regression analysis was employed to evaluate the hazard ratios of those risk factors on repeated keratoplasty. RESULTS:A total of 9,452 cases of corneal transplantation occurred from January 2006 to December 2016. The average annual incidence of corneal transplantations was 1.694 per 100,000. The proportion of penetrating keratoplasty steadily decreased from 92.22% in 2006 to 77.81% in 2016. The average incidence of repeated keratoplasty among those who underwent corneal transplantation at least once was 43.24 per 1,000 person-years. Males had a greater incidence of repeated keratoplasty compared to females (males: 47.66 per 1,000, females: 36.04 per 1,000). The age group from 20 to 39 years demonstrated the lowest incidence of repeated keratoplasty at 24.94 per 1,000. Keratoconus had the lowest incidence of repeated keratoplasty (22.82 per 1,000). CONCLUSION:This study may provide a better understanding of corneal diseases, help predict disease burden, and plan health care systems accordingly in South Korea.https://doi.org/10.1371/journal.pone.0235233 |
| spellingShingle | Kyoung Yoon Shin Dong Hui Lim Kyungdo Han Tae-Young Chung Higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in South Korea: A nationwide population-based study. PLoS ONE |
| title | Higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in South Korea: A nationwide population-based study. |
| title_full | Higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in South Korea: A nationwide population-based study. |
| title_fullStr | Higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in South Korea: A nationwide population-based study. |
| title_full_unstemmed | Higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in South Korea: A nationwide population-based study. |
| title_short | Higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in South Korea: A nationwide population-based study. |
| title_sort | higher incidence of penetrating keratoplasty having effects on repeated keratoplasty in south korea a nationwide population based study |
| url | https://doi.org/10.1371/journal.pone.0235233 |
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